Results 61 to 70 of about 77,977 (289)

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source

The year in cardiology: arrhythmias and pacing. [PDF]

, 2020
During this last year, there has been much progress with regard to anticoagulant and ablation therapy for atrial fibrillation (AF). Apart from recently issued European Society of Cardiology Guidelines for the management of patients with supraventricular ...
Calkins, H, Camm, AJ, Lip, GYH, Schilling, R, Steffel, J   +4 more
core   +4 more sources

A Personalized, 3D Printed Polymeric Device for the Prevention of Post‐Myocardial Infarction Cardiac Remodeling

Advanced Healthcare Materials, EarlyView.
Myocardial infarction often leads to pathological remodelling and ventricular dilatation, key features of HFrEF. This study introduces a personalized, 3D‐printed cardiac restraint device (CARD) printed using rationally designed inks displaying the requested printability and mechanical properties.
Nicola Mansour, Daniel Cohn, Ishita Sarkar, Raja Alamore, Kareem Abd Rbo, Offer Amir, Dean Nachman   +6 more
wiley   +1 more source

Effect of Echocardiographic Epicardial Adipose Tissue Thickness on Success Rates of Premature Ventricular Contraction Ablation

Balkan Medical Journal, 2019
Background: Idiopathic premature ventricular contractions are frequently detected ventricular arrhythmias, and radiofrequency ablation is an effectively treatment for improving symptoms and eliminating premature ventricular contractions.
Selçuk Kanat, Bilge Duran Karaduman, Ahmet Tütüncü, Erhan Tenekecioğlu, Ferit Onur Mutluer, Nihal Akar Bayram   +5 more
doaj   +1 more source

Investigation of the cardiac effects of exercise testing on apparently healthy Boxer dogs

Journal of Veterinary Internal Medicine, 2023
Background Holter electrocardiographic monitoring is a cornerstone of diagnostic testing for arrhythmogenic cardiomyopathy (ACM) in Boxer dogs, but physical activity during monitoring is not controlled.
Deepmala Agarwal, Etienne Côté, Lynne O'Sullivan, Kathryn M. Meurs, Jörg Steiner   +4 more
doaj   +1 more source

Acquired heart block: A possible complication of patent ductus arteriosus in a preterm infant [PDF]

, 2008
A large patent ductus arteriosus (PDA) is a frequently encountered clinical problem in extremely low birth weight (ELBW) infants. It leads to an increased pulmonary blood flow and in a decreased or reversed diastolic flow in the systemic circulation ...
Andreas Holzinger, Baylen B, Bucci G, Christoph Döhlemann, Evans N, Georg Münch, Griffin JH, Hans-Georg Dietz, Holger Till, Limperopoulos C, Mendicini M, Monika Grasser, Rashmi Mittal, Skelton R, Walther FJ   +14 more
core   +1 more source

Conformable Microelectrode Arrays Integrated with a Scoop‐Shaped Slide‐Well for Dynamic Electrophysiological Profiling of Patient‐Derived Cardiac Organoids

Advanced Science, EarlyView.
A flexible, ultrathin multi‐channel microelectrode array (MEA) conformally integrated onto a curved slide‐well enables stable electrical interfacing with 3D cardiac organoids. The geometry‐guided self‐alignment allows simultaneous recording of extracellular field potentials and contractile motion from irregular, beating tissues.
Ye Seul Kim, Jeonghwa Jeong, Gyeonghwa Heo, Young Woo Kwon, Jeongha Lee, Yoon Ji Jeong, Gyu Tae Park, Seongdo Jeong, Ki Won Hwang, Murim Choi, Jinhong Shin, Suck Won Hong, Jae Ho Kim   +12 more
wiley   +1 more source

Complex patterns of spontaneous initiations and terminations of reentrant circulation in a loop of cardiac tissue

, 2008
A two-component model is developed that consists of a discrete loop of cardiac cells that circulates action potentials together with a cardiac pacing mechanism.
Anastasiou-Nana, Banville, Bub, C.K. Cheng, C.M. Baumgarten, Cain, Cain, Cain, Cao, Chay, Chen, Cheng, Cherry, Chialvo, Chow, Courtemanche, Courtemanche, Courtemanche, Cytrynbaum, D.M. Chan, De Bakker, Derksen, Downar, Elaydi, Fox, Fox, Frame, Gilmour, Girouard, Glass, H. Sedaghat, Hall, Harris, Hwang, Ito, J.W. Cain, Jack, Jalife, Kalb, Keener, Kocic, Koller, Koller, Krebs, Kunysz, Lampert, Liebovitch, Lown, M.A. Wood, Manios, Mickens, Mines, Mitchell, Moe, Nagai, Nolasco, Otani, Plonsey, Qu, Quan, Sedaghat, Sedaghat, Stein, Stubna, Ten Tusscher, Vinet, Watanabe, Watanabe, Winkle, Wood, Wood, Wood   +71 more
core   +1 more source

Gene Transfer of Engineered Calmodulin Alleviates Ventricular Arrhythmias in a Calsequestrin-Associated Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia [PDF]

, 2018
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a familial arrhythmogenic syndrome characterized by sudden death. There are several genetic forms of CPVT associated with mutations in genes encoding the cardiac ryanodine receptor (RyR2 ...
Belevych, Andriy E, Bonilla, Ingrid, Davis, Jonathan P, Gy\uf6rke, S\ue1ndor, Ho, Hsiang-Ting, Knollmann, Bjorn C, Liu, Bin, Priori, Silvia G, Radwa\u144ski, Przemys\u142aw B, Shettigar, Vikram, Tikunova, Svetlana B, Volpe, Pompeo, Walton, Shane D   +12 more
core   +1 more source

Organ‐Specific and Conserved Regulatory Logic Orchestrates Gene Expression in the Embryonic Mesothelium

Advanced Science, EarlyView.
Integrated multi‐omic profiling maps the gene‐regulatory landscape of the coelomic mesothelium across heart, lung, and pancreas. A cardiac‐restricted regulatory program is uncovered in which TBX20 activates heart mesothelial (epicardial) cis‐regulatory elements, while MAF emerges as a conserved regulator of mesothelial identity.
Quang Minh Dang, Nicola Smart, Andia Nicole Redpath, Joaquim Miguel Vieira   +3 more
wiley   +1 more source