Results 111 to 120 of about 32,259 (328)

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Premature ventricular complexes in the absence of identifiable heart disease. [PDF]

, 1981
J B Kostis, Katherine McCrone, Abel E. Moreyra, S. Gotzoyannis, N M Aglitz, Nalin Natarajan, Peter T. Kuo   +6 more
openalex   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source

Supraventricular Tachycardia Conversion as a Response in Ventricular Premature Complexes

JACC: Case Reports
In 3 similar cases of supraventricular tachycardia, rhythm presented the same conversion mode. In 1 case, tachycardia was terminated with atrial activation, while entrainment maneuvers during an electrophysiology study revealed the same response and ...
Konstantinos Tampakis, MD, Evangelia-Erasmia Papakonstantinou, MD, Alexandros Sykiotis, MD, Sokratis Pastromas, MD, George Andrikopoulos, MD   +4 more
doaj   +1 more source

Deletion of heat shock protein 60 in adult mouse cardiomyocytes perturbs mitochondrial protein homeostasis and causes heart failure. [PDF]

, 2020
To maintain healthy mitochondrial enzyme content and function, mitochondria possess a complex protein quality control system, which is composed of different endogenous sets of chaperones and proteases.
Chen, Ju, Duan, Yaoyun, Fan, Feifei, Fang, Xi, Huang, Lei, Jia, Nan, Li, Yali, Liu, Jie, Ouyang, Kunfu, Tang, Huayuan, Trexler, Christa, Wang, Gang, Wang, Hong, Yang, Feili   +13 more
core  

Ethmozin, a new antiarrhythmic drug for suppressing ventricular premature complexes. [PDF]

, 1980
Philip J. Podrid, A. A. Lyakishev, Bernard Lown, Н. А. Мазур   +3 more
openalex   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Recovery of cardiomyopathy induced by ventricular premature beats of paraHisian origin after successful radiofrequency catheter ablation

Türk Kardiyoloji Derneği Arşivi, 2017
A 51-year-old male patient presented with frequent and symptomatic premature ventricular complexes (PVCs) that had induced cardiomyopathy. Radiofrequency (RF) catheter ablation of the origin of the PVCs was planned and the patient underwent ...
Gökhan Aksan, Ali Elitok, Mehmet Tezcan, Ahmet Kaya Bilge, Kamil Adalet   +4 more
doaj   +1 more source

The emerging role of Nrf2 in heart failure: From cardioprotection to therapeutic approaches

ESC Heart Failure, EarlyView.
Nrf2 signalling is impaired in heart failure, contributing to oxidative stress, mitochondrial dysfunction, and ferroptosis, which drive neurohormonal activation, inflammation, and ischaemia‐reperfusion injury. This loss of Nrf2 activity exacerbates hypertension, diabetic cardiomyopathy, and cardiotoxicity, accelerating progression to overt heart ...
Emiliano Fiori, Sergio Davinelli, Armando Ferrera, Alessandro Medoro, Carlo Barsali, Allegra Battistoni, Maurizio Volterrani, Massimo Volpe, Luciano Saso, Speranza Rubattu   +9 more
wiley   +1 more source

Co‐occurrence of late potential and discrete prepotential on ablation site in a case of cardiac crux located premature ventricular complexes successfully ablated within the middle cardiac vein

Journal of Arrhythmia, 2019
Some premature ventricular complexes (PVCs) originate from the coronary venous system. The great cardiac vein and the anterior cardiac vein are the most frequent localizations.
Kamil Gulsen, Fatih Bayrak, Baris Akdemir, Veli Polat, Hasan Ali Barman, Orhan Ince, Ertugrul Okuyan   +6 more
doaj   +1 more source