Results 141 to 150 of about 99,627 (293)

What can be done virtually? A modified Delphi study offering guidance on virtual companion animal physical examinations

Veterinary Record, EarlyView.
Abstract Background The inability to adopt a hands‐on approach can be viewed as a limitation to provide veterinary care virtually. The objective of this study was to establish guidance to support the remote delivery of a companion animal physical examination by video. Methods A modified approach to the Delphi method was followed.
Rosalie Fortin‐Choquette, Jason B. Coe, Cathy Bauman, Lori M. Teller   +3 more
wiley   +1 more source

ECG‐TransCovNet: A hybrid transformer model for accurate arrhythmia detection using Electrocardiogram signals

CAAI Transactions on Intelligence Technology, EarlyView.
Abstract Abnormalities in the heart's rhythm, known as arrhythmias, pose a significant threat to global health, often leading to severe cardiac conditions and sudden cardiac deaths. Therefore, early and accurate detection of arrhythmias is crucial for timely intervention and potentially life‐saving treatment.
Hasnain Ali Shah, Faisal Saeed, Muhammad Diyan, Nouf Abdullah Almujally, Jae‐Mo Kang   +4 more
wiley   +1 more source

Reproductive Challenges of the Ageing Female: A Comprehensive Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Changes in societal norms over the last few decades have resulted in novel family planning trends, notably delayed childbearing and increased maternal age at the birth of the first child. Despite advances in reproductive medicine, ageing poses significant challenges.
Sofia Bitzika, Meletios P. Nigdelis, Angelos Daniilidis, Erich‐Franz Solomayer, Irene Lambrinoudaki, Efstratios M. Kolibianakis, Dimitrios G. Goulis   +6 more
wiley   +1 more source

Cardiac magnetic resonance of healthy children and young adults with frequent premature ventricular complexes

, 2007
OBJECTIVE: To assess whether magnetic resonance imaging could detect any cardiac morphological or functional myocardial alterations in healthy children and young adults with ventricular arrhythmias. METHODS: Twenty-three subjects (14 male, mean age 15.
Pardeo, Manuela, Luigi Natale, Filippo Crea, Lanza, Gaetano Antonio, Alfonso Sestito, Crea, Francesca, Gabriella De Rosa, Fabio Infusino, Gregory A Sgueglia, Delogu, Angelica Bibiana, Angelica Delogu, Natale, Luigi, Infusino, Fabio, Fulvio Bellocci, Gaetano A Lanza, Bellocci, Fulvio, De Rosa, Gabriella, Manuela Pardeo, Sestito, Alfonso, Sgueglia, Gregory Angelo   +19 more
core   +1 more source

Safety of Venom Immunotherapy in Pregnancy: A Multicentre Study

Allergy, EarlyView.
Venom immunotherapy (VIT) during pregnancy, when maintenance dose is well tolerated, can be continued. No increased risk of adverse effects to VIT or safety concerns for the pregnancy or the newborns were observed. No decreased efficacy of VIT, in case of re‐stings, was reported.
Matteo Martini, Giovanna Sfriso, Valerio Pravettoni, Marina Mauro, Donatella Preziosi, Francesca Vettorato, Giuseppe Lucchini, Mauro Pagani, Iuliana Badiu, Maria Pia Dolcher, Francesco Gaeta, Pietro Galati, Elisa Meucci, Elide Pastorello, Vincenzo Patella, Stefano Pucci, Chiara Roncallo, Eleonora Savi, Livio Simioni, Maria Beatrice Bilò, Patrizia Bonadonna   +20 more
wiley   +1 more source

Diltiazem N‐oxide, a novel ischaemia‐activated prodrug, prevents ischaemia‐induced ventricular fibrillation without off‐target adverse effects

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Ventricular fibrillation (VF) in coronary heart disease accounts for up to 70% of sudden cardiac death. We examined whether diltiazem N‐oxide (DNO) has ischaemia‐selective antiarrhythmic activity. Experimental Approach Randomised and blinded experiments were performed in rat isolated hearts and in anaesthetised rats to ...
Louise M. Hesketh, Gabriel A. Watson, Francesca Mazzacuva, Zoe Hoare, Thomas R. Eykyn, Michael J. Curtis   +5 more
wiley   +1 more source

Endothelium‐ and epithelium‐derived novel endogenous catecholamines as modulators of the autonomic nervous system

British Journal of Pharmacology, EarlyView.
Abstract Catecholamines are classically viewed as neuronal transmitters and adrenal hormones; however, accumulating evidence demonstrates that sources other than nerve fibres and adrenal medulla play a fundamental role in local organ regulation. Physiological paradoxes, such as preserved organ function after denervation or transplantation, challenge a ...
Mariana G. de Oliveira, Edson Antunes, Fabiola Zakia Monica, Gilberto De Nucci   +3 more
wiley   +1 more source

Ablation of premature ventricular complexes originating from the left ventricular outflow tract using a novel automated pace-mapping software

, 2010
Pace-mapping is an important tool during the ablation of premature ventricular complexes (PVCs) or ventricular tachycardia. The automated pace mapping system software (PaSo module, CARTO XP v9, Biosense/Webster) allows direct comparisons between paced ...
T. Tahin, I. Osztheimer, G. Széplaki, SZ. Szilágyi, T. Bettenbuch, M. Srej, L. Gellér, B. Merkely   +7 more
core   +1 more source

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

British Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux, Solenn Gousset, Beltrán Alvarez, Monica Baiula, Wouter Bakker, Andrea Bedini, Monir Bertayli, Divakar Budda, Robert Carr, Elisabetta Cuna, Óscar Díaz, Nina Donner, Jesús Giraldo, Geert‐Jan Groeneveld, Berfin Gülave, David Guydan, Hemme Hijma, Rafael Maldonado, Pedro Renault, Carlos Rinaudo, Jeroen Elaissaiss‐Schaap, Athan Spiros, Sara Stoeber, Petri Takkala, Daan van Valkengoed, Coen van Hasselt, Elizabeth (Liesbeth) CM de Lange   +26 more
wiley   +1 more source

Immune checkpoint inhibitor‐induced arrhythmias: Mechanistic insights from clinical and preclinical studies

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, but their efficacy continues to be limited by immune‐related adverse events. Among these, ICI‐induced cardiac arrhythmias are increasingly recognised as a major adverse reaction, encompassing a broad spectrum of clinical phenotypes, including conduction blocks, atrial fibrillation and
Anand R. Ramalingam, Zoltán Márton Köhler, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source