Results 221 to 230 of about 32,259 (328)

Cardiovascular Challenges in Chronic Lymphocytic Leukemia (CLL) Patients Undergoing Bruton Tyrosine Kinase (BTK) Inhibitor Therapy

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Background/Objectives Bruton tyrosine kinase inhibitors (BTKis) have revolutionized treatment for chronic lymphocytic leukemia (CLL), but cardiovascular (CV) toxicities pose significant challenges. Second‐generation BTKis offer improved target specificity, yet CV risks persist.
Stefano Oliva, Stefano Molica
wiley   +1 more source

Successful catheter ablation of ventricular premature complexes from the right atrial side of the atrioventricular septum with good contact force

open access: gold, 2018
Marina Arai   +6 more
openalex   +1 more source

Lateralizing value of interictal epileptiform discharges and other parameters in hypothalamic hamartoma

open access: yesEpilepsia, Volume 66, Issue 3, Page 662-673, March 2025.
Abstract Objective Hypothalamic hamartomas (HHs) are associated with pharmacoresistant epilepsy. Stereotactic radiofrequency thermocoagulation (SRT) shows promise as a disconnecting intervention. Although magnetic resonance imaging (MRI) is typically used to determine the attachment and intervention side, it presents challenges in cases of bilaterally ...
Friederike Niedermoser   +7 more
wiley   +1 more source

Rare dysfunctional SCN2A variants are associated with malformation of cortical development

open access: yesEpilepsia, Volume 66, Issue 3, Page 914-928, March 2025.
Abstract Objective SCN2A encodes the voltage‐gated sodium (Na+) channel α subunit NaV1.2, which is important for the generation and forward and back propagation of action potentials in neurons. Genetic variants in SCN2A are associated with a spectrum of neurodevelopmental disorders.
Jérôme Clatot   +19 more
wiley   +1 more source

Strain Analysis in Patients with Frequent Premature Ventricular Complexes and Preserved Left Ventricular Function Undergoing Ablation. [PDF]

open access: yesJ Clin Med, 2023
Jamé S   +9 more
europepmc   +1 more source

Long‐read sequencing of recurrent FGF12 duplications in epilepsy: Insights into structural mechanisms and aberrant isoforms

open access: yesEpilepsia, EarlyView.
Abstract Objective Fibroblast growth factor 12 (FGF12), a member of the fibroblast homologous factor family, plays a key role in the modulation of voltage‐gated sodium (Nav) channels. Pathogenic variants in the FGF12 gene leading to a gain‐of‐function mechanism and partial duplication encompassing the FGF12 gene leading to a loss‐of‐function mechanism ...
Jade Fauqueux   +18 more
wiley   +1 more source

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