Diabetic Foot Ulcers Are Clinical Marker of Disease Burden in People With Diabetes and Heart Failure
ABSTRACT Introduction Diabetic foot ulcers and heart failure are severe complications of diabetes mellitus, both associated with high morbidity and mortality. Whether diabetic foot ulcers worsen prognosis in people with heart failure remains unclear.
A. Rumanes +4 more
wiley +1 more source
Response to equine cardiac adverse events during sports
Summary Cardiac adverse events and sudden death are a feared scenario for equine veterinarians, with serious consequences for animal health, riders' safety and the social licence to operate equestrian sports. The response to equine cardiac adverse events (CAEs) during sports is poorly defined.
C. Navas de Solis +9 more
wiley +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Effectiveness and Safety of Intramyocardial Needle Ablation for Refractory Ventricular Tachycardia and Premature Ventricular Complexes: A Systematic Review and Meta-Analysis. [PDF]
Gupta K +8 more
europepmc +1 more source
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo +7 more
wiley +1 more source
An implantable phototriggered prodrug depot patch (iPDP) is presented that enables actively programmable drug release post‐implantation. Covalently conjugated prodrug ensures minimal leakage; illumination parameters serve as a code to precisely control dose per release.
Haipeng Lu +10 more
wiley +1 more source
Association of Systemic Sclerosis With Premature Ventricular Complexes and Cardiac Arrest: A National Inpatient Sample Analysis for 2021. [PDF]
Nwogwugwu E +9 more
europepmc +1 more source
Engineering CAR‐Macrophages With Advanced Delivery Systems for Tissue Repair
This review highlights how engineered macrophages equipped with chimeric antigen receptors (CAR) guide tissue repair by recognizing disease‐related targets, clearing harmful cells, and reshaping local immune environments. It summarizes macrophage biology, CAR design, delivery platforms, and functionalization strategies, and discusses emerging ...
Yixin Zhang +8 more
wiley +1 more source
Coronary Artery Identification With Intracardiac Echocardiography and Integration on 3D Mapping During Radiofrequency Ablation of Premature Ventricular Complexes. [PDF]
Dell'Aquila A +3 more
europepmc +1 more source
35 Individuals With HUWE1‐Related Neurodevelopmental Disorder and Suggested Clinical Evaluations
ABSTRACT HUWE1 (HECT, UBA, and WWE Domain Containing E3 Ubiquitin Protein Ligase1, OMIM 300697), located at Xp11.22, encodes a ubiquitin ligase that is highly conserved across species. Genetic variants in HUWE1 described in multiple independent studies cause X‐linked intellectual disability, including in the patients identified by Juberg, Marsidi, and ...
Mindy H. Li +25 more
wiley +1 more source

