Results 61 to 70 of about 1,408,623 (295)

Strain Analysis in Patients with Frequent Premature Ventricular Complexes and Preserved Left Ventricular Function Undergoing Ablation

, 2023
Background: Frequent premature ventricular complexes (PVCs) can cause PVC-induced cardiomyopathy. The value of PVC ablation in patients with preserved left ventricular function in the low–normal range (ejection fraction: 50–55%) is not established ...
Zhigang Liu, Troy Labounty, Michael Ghannam, Rakesh Latchamsetty, Theodore Kolias, Krit Jongnarangsin, Jackson Liang, Fred Morady, Frank Bogun, Sina Jamé   +9 more
core   +1 more source

A Second Pathogenic Protein, PolyGN2C‐iso2, Reveals a Dual‐Protein Pathology in Neuronal Intranuclear Inclusion Disease

Advanced Science, EarlyView.
This study reveals that NOTCH2NLC transcript variant 2 generates PolyGN2C‐iso2, an aggregating protein present within intranuclear inclusions of NIID patient tissues. A novel mouse model expressing PolyGN2C‐iso2 recapitulates white matter abnormalities and cognitive deficits, mechanistically linked to mitochondrial dysfunction. These findings support a
Kang Zhang, Wenhao Ma, Yi Zhou, Zhijie Wu, Pan Gao, Hongze Niu, Hongfei Tai, Tianyi Zhao, Zheyue Dong, Li Li, Yan Zhang, An Wang, Si Shen, Yueyang Li, Sifei Yu, Yan Peng, Wang Sheng, Xiaoyan Dong, Hua Pan, Kaibin Shi, Magdalena J. Koziol, Xiaobing Wu, Zaiqiang Zhang   +22 more
wiley   +1 more source

Sudden cardiac arrest in an athlete due to dilated cardiomyopathy masquerading as athlete's heart: a case report

Frontiers in Cardiovascular Medicine
BackgroundSudden cardiac arrest (SCA) in athletes is a rare but catastrophic event, most often associated with underlying cardiac pathology. Differentiating physiological remodeling (“athlete's heart”) from pathological conditions such as cardiomyopathy ...
Gita Pangestu Hapsari, Brian Mendel, Ira Posangi, Dony Yugo Hermanto   +3 more
doaj   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

The Relationship between Depression Symptoms and Physical Activity in Children with Idiopathic Ventricular Extrasystoles

Medicina
Background and Objectives: Depression in childhood often co-occurs with anxiety disorders and a range of somatic symptoms. Recent studies have identified physical activity as a target for preventing the onset of depression.
Rita Kunigeliene, Odeta Kinciniene, Vytautas Usonis, Sigita Lesinskiene   +3 more
doaj   +1 more source

Prognostic significance of accelerated ventricular response during radiofrequency ablation of premature ventricular complexes

Indian Pacing and Electrophysiology Journal, 2020
Background: Accelerated ventricular response is frequently observed during radiofrequency ablation (RFA) of premature ventricular complexes (PVCs). We hypothesized that acceleration indicates an appropriate site and adequate injury to the arrhythmogenic ...
Sirish Chandra Srinath Patloori, Anand Manickavasagam, David Chase, John Roshan   +3 more
doaj   +1 more source

A Comprehensive Review of Left Ventricular Summit Ventricular Arrhythmias

Journal of Tehran University Heart Center, 2022
The catheter ablation of idiopathic ventricular arrhythmias is accepted as a first-line treatment as it successfully eliminates about 90.0% of such arrhythmias.
Farzad Kamali, Majid Haghjoo, Yeganeh Pasebani, Abolfath Alizadehdiz, Zahra Emkanjoo, Amirfarjam Fazelifar, Farzad Masoudkabir, Ala Keykhavani, Shabnam Madadi   +8 more
doaj   +1 more source

Premature Ventricular Complex-induced Cardiomyopathy

Arrhythmia & Electrophysiology Review, 2018
Premature ventricular complex-induced cardiomyopathy is a potentially reversible condition in which left ventricular dysfunction is induced by the occurrence of frequent premature ventricular complexes (PVCs). Various cellular and extracellular mechanisms and risk factors for developing cardiomyopathy in this context have been suggested but the exact ...
Jorge G, Panizo, Sergio, Barra, Greg, Mellor, Patrick, Heck, Sharad, Agarwal   +4 more
openaire   +2 more sources

Multivariate model to assess the variables correlated with premature ventricular complexes.

, 2018
Multivariate model to assess the variables correlated with premature ventricular complexes.
Alice Tatsuko Yamada (5775098), Gisela Tunes da Silva (5775101), Cesar José Grupi (766202), Wilma Noia Ribeiro (5775095), Alfredo Jose Mansur (5775104)   +4 more
core   +1 more source

PARP Inhibitors plus Anlotinib as Bridging Therapy for Armored CAR‐T Cells in Ovarian Cancer Enhances Infiltration and Antitumor Efficacy

Advanced Science, EarlyView.
This study shows that a PARP inhibitor combined with anlotinib, administered as bridging therapy, preconditions the tumor microenvironment to enhance the infiltration and antitumor activity of subsequently infused CAR‐T cells across preclinical ovarian cancer models, supporting bridging therapy as a promising strategy to address limited CAR‐T cell ...
Huayi Li, Minghua Xiang, Qiuyang Xu, Jiahao Liu, Xiaofei Jiao, Wei Mu, Xiaoying Lv, Kangjia Tao, Yu Xu, Dongchen Zhou, Wenjian Gong, Danmei Yan, Yixin Hu, Sen Xu, Bingbing Zhao, Jundong Li, Yongkang Gai, Guang Hu, Li Zhu, Qinglei Gao, Yong Fang   +20 more
wiley   +1 more source