Results 191 to 200 of about 85,801 (287)

Comparison of severe maternal morbidity between pregnancy with subclinical hypothyroidism and overt hypothyroidism

open access: yesActa Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 3, Page 499-507, March 2026.
In this cross‐sectional study, pregnancy with subclinical hypothyroidism was associated with higher rates of severe maternal morbidity at delivery compared with overt hypothyroidism, including cardio‐pulmonary morbidity and eclampsia. This association was especially seen among younger age, Black individuals, prepregnant hypertension, and obesity ...
Laurel S. Aberle   +10 more
wiley   +1 more source

QT Myopia and Cardiac Safety: Expanding the Aperture of Arrhythmia Assessment in Early Phase Drug Development

open access: yesClinical and Translational Science, Volume 19, Issue 3, March 2026.
ABSTRACT Regulatory agencies such as the Food and Drug Administration (FDA), European Medicines Agency (EMA), Health Canada, and the Japanese Pharmaceutical and Medical Device Agency (PMDA) provide scientific and public health guidance with cardiac safety being paramount in drug development of new investigational products (IP).
Robert M. Lester   +2 more
wiley   +1 more source

Impact of Coronary Microvascular Dysfunction on Left Ventricular Function After Percutaneous Coronary Intervention: Assessment With Combined Dipyridamole‐Exercise Stress and Myocardial Strain/Work

open access: yesEchocardiography, Volume 43, Issue 3, March 2026.
Decreased coronary flow velocity reserve (CFVR) was correlated with left ventricular (LV) dysfunction after percutaneous coronary intervention (PCI), as assessed via dipyridamole‐exercise stress echocardiography (DExE). This dysfunction was characterized by lower myocardial strain/work index and worse 1‐year Seattle Angina Questionnaire (SAQ) scores ...
Wanyu Zhao   +12 more
wiley   +1 more source

Alterations of sarcoplasmic reticulum-mediated Ca<sup>2+</sup> uptake in a model of premature ventricular contraction (PVC)-induced cardiomyopathy. [PDF]

open access: yesMol Cell Biochem, 2023
Balderas-Villalobos J   +9 more
europepmc   +1 more source

Treg cells retain stable lineage commitment during pregnancy in mice after late gestation inflammatory challenge

open access: yesImmunology &Cell Biology, Volume 104, Issue 3, Page 276-311, March 2026.
In this study, we used Foxp3‐fatemapping mice to examine the cell lineage stability of Treg cells in pregnancy. Ex‐Foxp3 cells were identified in gestational tissues. However, Treg cells retained lineage stability with no increased ex‐Foxp3 generation, regardless of inflammatory challenges that induce preterm birth.
Kerrie L Foyle   +6 more
wiley   +1 more source

A Premature Ventricular Contraction Associated With Transient Worsening Pulsus Alternans: A Case Report. [PDF]

open access: yesCureus, 2021
Trongtorsak A   +4 more
europepmc   +1 more source

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