Results 121 to 130 of about 160,741 (387)
Obesity Science & PracticeBackground Obesity increases the risk of breast cancer by approximately 10% for every 5‐unit increase in body mass index (BMI), underscoring its role as a key modifiable risk factor.
Marco Yusef +8 more
doaj +1 more source
C-reactive protein: associations with haematological variables, cardiovascular risk factors and prevalent cardiovascular disease [PDF]
, 2003 C-reactive protein (CRP) has been proposed as a risk factor for cardiovascular disease; however, this association is confounded by mutual relationships with both classical and haematological cardiovascular risk factors. We, therefore, measured CRP with a
Ann Rumley +31 more
core +1 more source
The molecular landscape of premenopausal breast cancer
Breast Cancer Research, 2015 Breast cancer in premenopausal women (preM) is frequently associated with worse prognosis compared to that in postmenopausal women (postM), and there is evidence that preM estrogen receptor-positive (ER+) tumors may respond poorly to endocrine therapy ...
Serena G. Liao +13 more
semanticscholar +1 more source
Risk of Cancer With Hormone Replacement Therapy: A Narrative Review
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.ABSTRACT Hormone replacement therapy (HRT) remains the cornerstone of menopausal symptom management, effectively alleviating vasomotor symptoms and genitourinary syndrome, whilst mitigating long‐term risks such as osteoporosis. However, despite an increasing body of evidence on the relative safety of HRT, earlier studies that demonstrated an increased ...
Gabriella Yongue +3 more
wiley +1 more source
Decreased risk of breast cancer associated with oral bisphosphonate therapy [PDF]
, 2012 Preclinical studies and adjuvant trials using bisphosphonates have found them to have an antitumor effect. Although major advances have been made in chemoprevention strategies with selective estrogen receptor modulators and aromatase inhibitors, their ...
Brufsky, A, Mathew, A
core +2 more sources
The Lancet Oncology, 2013 BACKGROUND Associations between circulating concentrations of oestrogens, progesterone, and androgens with breast cancer and related risk factors in premenopausal women are not well understood.
Endogenous Hormones +31 more
semanticscholar +1 more source
Asia-Pacific Journal of Clinical Oncology, EarlyView.We selected breast cancer‐specific DNA methylation markers using The Cancer Genome Atlas (TCGA). We analyzed the methylation and expression patterns of candidate genes in breast cancer cell lines, ctDNA, and tissue samples. The relationship between ctDNA methylation markers and the clinicopathological features of breast cancer patients was investigated.
Young Ju Jeong +6 more
wiley +1 more source
Managing menopausal symptoms and associated clinical issues in breast cancer survivors [PDF]
, 2017 Objective: Review evidence to guide management of menopausal signs and symptoms in women after breast cancer and make recommendations accordingly. Evidence: Randomized controlled clinical trials, observational studies, evidence-based guidelines, and
Davis, Susan R. +5 more
core +1 more source
The Pharmacogenomics Journal, 2014 Tamoxifen is the standard-of-care treatment for estrogen receptor-positive premenopausal breast cancer. We examined tamoxifen metabolism via blood metabolite concentrations and germline variations of CYP3A5, CYP2C9, CYP2C19 and CYP2D6 in 587 ...
Pilar H. Saladores +20 more
semanticscholar +1 more source
Acta Obstetricia et Gynecologica Scandinavica, EarlyView.Women aged 50 or above, who have undergone mid‐urethral sling surgery 10–14 years earlier for stress urinary incontinence, report more pelvic pain than age‐matched women. Other lower urinary tract symptoms also seem to be more prevalent in women 50 years or above with previous surgery.
Anna Lundmark Drca +4 more
wiley +1 more source