Results 71 to 80 of about 160,741 (387)

Review of: "Neoadjuvant chemotherapy modifies thyroid function in postmenopausal but not premenopausal women with breast cancer" [PDF]

, 2022
Gábor Rubovszky
openalex   +1 more source

Pharmacogenetic CYP2B6 variants affect steroid hormone metabolism in human breast cancer cells

British Journal of Clinical Pharmacology, EarlyView.
Common genetic CYP2B6 variants correlate with adverse breast cancer outcome. The oestrogen metabolites estriol and 16‐epiestriol, which are formed downstream of CYP2B6‐catalysed 16α/β‐hydroxytestosterone, may be linked to elevated breast cancer risk and might increase due to the demonstrated CYP2B6 variants‐related metabolic shifts.
Marco Hoffmann, Julian Peter Müller, Stefan Düsterhöft, Sabrina Yamoune, Katja Susanne Just, Julia Carolin Stingl   +5 more
wiley   +1 more source

Ovarian Function Suppression With Luteinizing Hormone-Releasing Hormone Agonists for the Treatment of Hormone Receptor-Positive Early Breast Cancer in Premenopausal Women

Frontiers in Oncology, 2021
Chemotherapy and endocrine therapies are mainstays of treatment for early and advanced hormone receptor-positive (HR+) breast cancer. In premenopausal women with HR+ tumors, the benefits of adding ovarian function suppression (OFS) to endocrine therapy ...
Yen-Shen Lu, Andrea Wong, Hee-Jeong Kim
doaj   +1 more source

Adjuvant exemestane with ovarian suppression in premenopausal breast cancer.

New England Journal of Medicine, 2014
BACKGROUND Adjuvant therapy with an aromatase inhibitor improves outcomes, as compared with tamoxifen, in postmenopausal women with hormone-receptor-positive breast cancer.
O. Pagani, B. Walley, G. Fleming, M. Colleoni, I. Láng, H. Gómez, C. Tondini, H. Burstein, M. Goetz, E. Ciruelos, V. Stearns, H. Bonnefoi, S. Martino, C. Geyer, C. Chini, F. Puglisi, S. Spazzapan, T. Ruhstaller, E. Winer, B. Ruepp, S. Loi, A. Coates, R. Gelber, A. Goldhirsch, M. Regan, P. Francis   +25 more
semanticscholar   +1 more source

Shared Versus Unique Features of Neural Activation During Cognitive Flexibility Across Restrictive Eating Disorder Presentations

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Restrictive eating disorders (EDs), including anorexia nervosa (AN) and atypical AN (Atyp‐AN), are often associated with cognitive rigidity that can impede treatment. The dorsolateral prefrontal cortex (dlPFC) plays a central role in cognitive control, but it remains unclear whether its activation during cognitive flexibility will ...
Adrienne L. Romer, Lauren Breithaupt, Meghan Slattery, Felicia Petterway, Lauren Lindman, Jason Scott, Meghan Lauze, Mia Cravitz, Zara Poon, Siddarth Seenivasa, Sarah Naticchia, Kristin N. Javaras, David Alperovitz, Jennifer J. Thomas, Elizabeth A. Lawson, Diego A. Pizzagalli, Franziska Plessow, Poornima Kumar, Madhusmita Misra, Kamryn T. Eddy   +19 more
wiley   +1 more source

Body mass index had different effects on premenopausal and postmenopausal breast cancer risks: a dose-response meta-analysis with 3,318,796 subjects from 31 cohort studies

BMC Public Health, 2017
BackgroundThere is sufficient evidence supporting a relationship between increased body mass index (BMI) and an increased risk for breast cancer among postmenopausal women. However, most studies have found a decreased risk for premenopausal breast cancer.
Yanzi Chen, Li Liu, Quan Zhou, M. Imam, Jialin Cai, Yaxuan Wang, Minjie Qi, P. Sun, Z. Ping, Xiaoli Fu   +9 more
semanticscholar   +1 more source

The cervico‐vaginal DNA methylation WID‐qEC test: An epigenetic marker associated with ovarian cancer in the absence of endometrial and cervical cancer

International Journal of Cancer, EarlyView.
What's New? The DNA methylation‐based WID‐qEC test has been validated for the accurate detection of endometrial and cervical cancers using cervico‐vaginal samples. However, a small proportion of women test positive despite the absence of these cancers. This study explored the associated biological and clinical characteristics to inform potential follow‐
Elisa Redl, Chiara Herzog, Charlotte Vavourakis, James Barrett, Allison Jones, Iona Evans, Daniel Reisel, Ranjit Manchanda, Line Bjørge, Michal Zikan, David Cibula, Twana Alkasalias, Angelique Flöter Rådestad, Kristina Gemzell‐Danielsson, Louis Dubeau, Nicola MacDonald, Davor Jurkovic, Nora Pashayan, Martin Widschwendter   +18 more
wiley   +1 more source

Correlation of mandibular ramus height and width with osteoporosis

Journal of Oral and Maxillofacial Radiology, 2017
Context: Osteoporosis is a disease of bone with distinctive decrease in bone mineral density and bone strength. It is important to diagnose it early before the patient presents to the emergency with a fracture hip or spine.
Dur-e-Shahwar Rehman, Talat Yasmeen, Nabeel Qamar   +2 more
doaj   +1 more source

Testosterone Therapy in Premenopausal Women

Seminars in Reproductive Medicine, 2006
Testosterone therapy for postmenopausal women and women with surgical menopause, albeit controversial, is becoming more widespread. However, only limited data are available to support its use in premenopausal women. Androgens have important biological roles in young women, influencing bone and muscle mass, mood and well-being, and libido ...
Kalantaridou, S. N., Calis, K. A.
openaire   +3 more sources

Non-alcoholic fatty liver disease connections with fat-free tissues: A focus on bone and skeletal muscle [PDF]

, 2017
The estimates of global incidence and prevalence of non-alcoholic fatty liver disease (NAFLD) are worrisome, due to the parallel burden of obesity and its metabolic complications. Indeed, excess adiposity and insulin resistance represent two of the major
Chiesa, Claudio, Donini, Lorenzo Maria, Lenzi, Andrea, Pacifico, Lucia, Poggiogalle, Eleonora   +4 more
core   +2 more sources