Results 151 to 160 of about 115,105 (293)

Mulberry Leaf Powder Supplemented with a Multi-Enzyme Premix Affects the Intestinal Microbiota-Metabolite-Immunity Axis and Nrf2/Keap1 Signaling in Juvenile <i>Acipenser schrenckii</i>: A Dose-Dependent Evaluation. [PDF]

Foods
Zhu W, Zhang N, Wang X, Xiong Y, Yang F, Wang Y.   +5 more
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Evaluation of copper feeding strategies and sources on nursery and finishing pig performance. [PDF]

Transl Anim Sci
Swanson SA, Woodworth JC, Tokach MD, Goodband RD, DeRouchey JM, Gaffield KN, Gebhardt JT, Cochrane R, Einarson M.   +8 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Effects of carvacrol- and thymol-based essential oil feed additives on carcass characteristics and breast meat quality of broilers with or without Salmonella challenge. [PDF]

Poult Sci
Naeem M, Tushar ZH, Raut R, Kumar R, Fatima A, Adhikari Y, Bailey M, Poudel S, Manjankattil S, Pacheco WJ, Rochell SJ, Bourassa DV.   +11 more
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Effect of carvacrol- and thymol-rich essential oil feed additives on colonization and persistence patterns of Salmonella in broiler chickens. [PDF]

Poult Sci
Naeem M, Manjankattil S, Poudel S, Adhikari Y, Bailey M, Wang J, Sulleyman K, Stokes T, Mejia W, Casco K, Rochell SJ, Pacheco WJ, Bourassa DV.   +12 more
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

STUDY ON THE DIFFERENT AMOUNTS OF AMINOVITAMIN PREMIX CONTENT IN THE SILKWORM, BOMBYX MORI L. ARTIFICIAL DIET

, 2012
A silkworm artificial diet created by the author, contained 38 % mulberry leaf powder, 34 % defatted soybean meal and the rest 28 % - corn starch, agar agar, citric acid, ascorbic acid, microelements and vitamins, antibiotic and preservatives was used in
Tzenov, Panomir, ЦЕНОВ, ПАНОМИР   +1 more
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source