Results 71 to 80 of about 655,699 (284)

RENAL‐CHIP: Rejection Evaluation via Non‐Invasive Analysis of Circulating Podocytes With Herringbone‐Chip Isolation Platform

Advanced Science, EarlyView.
RENAL‐CHIP converts 1 mL of peripheral blood into a biopsy‐equivalent readout of renal‐allograft fate. By magnetic capture and release of donor‐derived circulating podocytes through a herringbone microfluidic chip, 84% capture, 96% release and single‐cell RNA evidence of rejection‐specific immunity are achieved.
Juan Song, Yilong Liu, Zeyuan Zheng, Ming Zhu, Yuning Zou, Pei Liu, Yue Zheng, Xiyuan Yu, Jianzhong Zheng, Chen Shao, Huimin Zhang, Chaoyong Yang   +11 more
wiley   +1 more source

Prenatal diagnosis and early childhood outcome of fetuses with extremely large nuchal translucency

Molecular Cytogenetics, 2023
Objective To evaluate the prenatal and perinatal outcome of fetuses with extremely large nuchal translucency (eNT) thickness (≥ 6.5 mm). Methods 193 (0.61%) singleton fetuses with eNT were retrospectively included.
Hang Zhou, Xin Yang, CuiXing Yi, Huizhu Zhong, Simin Yuan, Min Pan, Dongzhi Li, Can Liao   +7 more
doaj   +1 more source

Parental Substance Abuse As an Early Traumatic Event. Preliminary Findings on Neuropsychological and Personality Functioning in Young Drug Addicts Exposed to Drugs Early. [PDF]

, 2016
open5noParental substance use is a major risk factor for child development, heightening the risk of drug problems in adolescence and young adulthood, and exposing offspring to several types of traumatic events.
Afifi, Aharonovich, Alati, Alati, American Psychiatric Association (APA), American Psychiatric Association (APA), Anda, Bada, Baer, Bailey, Baker, Barnard, Barr, Behnke, Bennett, Best, Bhide, Blagov, Blair, Bornovalova, Brand, Brown, Carmody, Chambers, Chapman, Chassin, Chassin, Chen, Cone, Connor, Cooper, Crean, Cruz, Cyr, Daniel, Day, Day, De Palo, Delaney-Black, Dennis, Derogatis, Derogatis, Dikmen, Edwards, Eiden, Eiden, Eiden, Eiden, El-Sheikh, El-Sheikh, Elkins, Engeland, Enoch, Ersche, European Monitoring Centre for Drugs Drug Addiction (EMCDDA), Evans, Eyler, Fals-Stewart, Farah, Farah, Fishbein, Fisher, Fisher, Ford, Frank, Fried, Giancola, Gibb, Glantz, Goldman, Goldschmidt, Goler, Grant, Griffith, Guttmacher Institute, Hackman, Hans, Hanson, Henry, Hicks, Hinrichs, Hurt, Hurt, Hussong, Hussong, Hussong, Jacobson, Jernigan, Johnston, Jutras-Aswad, Kearney, Kerns, Killinger, Kliewer, Klonoff-Cohen, Kodituwakku, Kokkevi, Konijnenberg, Kopera-Frye, Krueger, Langås, Leech, Lester, Lester, Lewis, Lewis, Li, Lingiardi, Lipina, Mackesy-Amiti, Malone, Marin-Avellan, Mattson, Maurage, May, Mayes, Mayes, McClelland, McGue, McNamee, Melchior, Meyers, Mezzacappa, Minnes, Moilanen, Mondini, Mondini, Morgan, Nigg, Noble, Noble, Noland, Noland, O'Brien, O'Connor, Obot, Olson, Olson, Pears, Posner, Prunas, Putnam, Rao, Rasmussen, Rasmussen, Richardson, Richardson, Riley, Rose-Jacobs, Rose-Jacobs, Rosenkranz, Rubes, Samhsa Office of Applied Studies (SAMHSA), Sarno, Savage, Schmid, Shedler, Shedler, Sheinkopf, Singer, Singer, Smith, Solowij, Stocco, Stone, Strathearn, Tapert, Tapert, Taplin, Tarter, Tarter, Thompson, Tonmyr, van der Kolk, Van Voorst, Vaske, Velez, Verdejo-García, Warner, Warner, Westen, Westen, Westen, Westen, Willford, Willford, Woon, Young   +187 more
core   +2 more sources

Hierarchical Channeled Graphitized Nanoarchitecture as a Diagnostic Platform for Maternal Fever Warning

Advanced Science, EarlyView.
This study presents a hierarchically channeled graphitized nanoarchitecture (HPGC‐Z67) as a novel nano‐diagnostic platform. It enables sensitive and efficient N‐glycan extraction from plasma, significantly reducing processing time and cost. The platform identifies pivotal N‐glycans to accurately differentiate between infectious and non‐infectious ...
Yiwen Lin, Ning Li, Heyuhan Zhang, Xufang Hu, Zhiqiang Liu, Chunhui Deng   +5 more
wiley   +1 more source

Phosphatidic Acid‐TRIM59‐Olig2 Signaling Couples Metabolic Dysfunction to Myelination Failure in PWMI

Advanced Science, EarlyView.
PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li, Yanan Liu, Meng Zhang, Yiwei Liu, Meiting Liu, Kaishen Zhu, Zhian Liu, Chao Ren, Ruiqin Yao   +8 more
wiley   +1 more source

Tracking of [14C]Polystyrene Nanoplastics in Pregnant Mice

Advanced Science, EarlyView.
This study investigates [14C]polystyrene nanoplastic ([14C]PS) translocation in late‐stage pregnant mice after intranasal (0.5 mg of [14C]PS on GD12, GD14, and GD16, n = 6) and intravenous administration (1.5 mg of [14C]PS on GD16, n = 6). 14C‐radiolabel allows quantitative tracking of unmodified polystyrene nanoplastics.
Olga Khaybullina, Pallavi Sarkhel, Outi M. Keinänen   +2 more
wiley   +1 more source

Role of fetal MRI in the evaluation of isolated and non-isolated corpus callosum dysgenesis: results of a cross-sectional study [PDF]

, 2017
PURPOSE: The aims of this study were to characterize isolated and non-isolated forms of corpus callosum dysgenesis (CCD) at fetal magnetic resonance imaging (MRI) and to identify early predictors of associated anomalies.
Antonelli, Amanda, Bernardo, Silvia, Catalano, Carlo, DE VITO, Corrado, Di Meglio, L, Giancotti, Antonella, Manganaro, Lucia, Marchionni, Enrica, Pizzuti, Antonio, Saldari, Matteo, Silvestri, E, Vinci, Valeria   +11 more
core   +1 more source

Deciphering the Impact of RAC1‐SPTAN1 in ARPKD Cystogenesis Using Multifaceted Models

Advanced Science, EarlyView.
Distal/connecting tubules expressing SLC8A1 have been suggested as a potential origin of ARPKD cysts. SPTAN1 has been identified as a key molecule in ARPKD cyst formation. Restoring SPTAN1 in PKHD1−/− organoids reduced cyst formation, normalized calcium levels, and decreased RAC1/c‐FOS expression, highlighting SPTAN1's role in ARPKD and the potential ...
Shohei Kuraoka, Yuhei Higashi, Suguru Saito, Solmaz Pourgonabadi, Honami Honjoh, Sho Ishigaki, Peter C. Harris, Lisa M. Satlin, Michifumi Yamashita, Ryuji Morizane   +9 more
wiley   +1 more source

P622: NIPS dilemma in the context of consanguinity: Considerations for counseling

Genetics in Medicine Open, 2023
Noura Osman, Kathryn Rice, Herman Hedriana, Krishna Singh   +3 more
doaj   +1 more source

Copy number variations associated with fetal congenital kidney malformations

Molecular Cytogenetics, 2020
Background Congenital anomalies of the kidney and urinary tract (CAKUT) constitute 20–30% of all congenital malformations. Within the CAKUT phenotypic spectrum, renal hypodysplasia (RHD) is particularly severe.
Meiying Cai, Na Lin, Linjuan Su, Xiaoqing Wu, Xiaorui Xie, Ying Li, Xuemei Chen, Yuan Lin, Hailong Huang, Liangpu Xu   +9 more
doaj   +1 more source