Results 21 to 30 of about 4,269,423 (255)

Analysis of Biomarkers for Congenital Heart Disease Based on Maternal Amniotic Fluid Metabolomics

Frontiers in Cardiovascular Medicine, 2021
Congenital heart disease (CHD) is the most common birth defect. The prenatal diagnosis of fetal CHD is completely dependent on ultrasound testing, but only ~40% of CHD can be detected.
Yahong Li, Yun Sun, Lan Yang, Mingtao Huang, Xiaojuan Zhang, Xin Wang, Xianwei Guan, Peiying Yang, Yan Wang, Lulu Meng, Ran Zhou, Xiaoyan Zhou, Chunyu Luo, Ping Hu, Tao Jiang, Zhengfeng Xu   +15 more
doaj   +1 more source

Prenatal hospitalization and compliance with guidelines for prenatal care. [PDF]

American Journal of Public Health, 1996
OBJECTIVES: This study examined the relationship between compliance with the US Public Health Service guidelines for prenatal care and the rate of prenatal hospitalization. METHODS: For all women admitted to a Boston referral center during January and February 1993 with a pregnancy of at least 18 weeks gestation (n = 1400), a proportional hazards ...
J S, Haas, S, Berman, A B, Goldberg, L W, Lee, E F, Cook   +4 more
openaire   +2 more sources

Optical genome mapping for detection of chromosomal aberrations in prenatal diagnosis

Acta Obstetricia et Gynecologica Scandinavica, 2023
Introduction Chromosomal aberrations are the most important etiological factors for birth defects. Optical genome mapping is a novel cytogenetic tool for detecting a broad range of chromosomal aberrations in a single assay, but relevant clinical ...
Qinxin Zhang, Yan Wang, Yiyun Xu, Ran Zhou, Mingtao Huang, Fengchang Qiao, Lulu Meng, An Liu, Jing Zhou, Li Li, Xiuqing Ji, Zhengfeng Xu, Ping Hu   +12 more
doaj   +1 more source

Pregnancy with Concomitant Chorioangioma and Placental Mesenchymal Dysplasia: A Rare Placental Abnormality

Case Reports in Obstetrics and Gynecology, 2013
Background. Pregnancy with concomitant chorioangioma and placental mesenchymal dysplasia (PMD) coexisting with a normal viable fetus is very rare. The literature was reviewed to explore the incidence and genetic origin of this condition. Case.
Wu Qichang, Wang Wenbo, Zheng Liangkai, Kong Hui, He Xiaoqin, Sun Li, Xu Yasong   +6 more
doaj   +1 more source

Systematic analysis of copy number variants of uncertain significance partially overlapping with the haploinsufficient or triplosensitive genes in clinical testing

Annals of Medicine, 2023
Background: Copy number variants of uncertain significance (VUS) has brought much distress for patients and great counselling challenges for clinicians.
Ran Zhou, Jiao Jiao, Yan Wang, Lulu Meng, Yiming Li, Yiyun Xu, Ping Hu, Zhengfeng Xu   +7 more
doaj   +1 more source

Detection rates of abnormalities in over 10,000 amniotic fluid samples at a single laboratory

BMC Pregnancy and Childbirth, 2023
Background A growing number of cytogenetic techniques have been used for prenatal diagnosis. This study aimed to demonstrate the usefulness of karyotyping, BACs-on-Beads (BoBs) assay and single nucleotide polymorphism (SNP) array in prenatal diagnosis ...
Sha Lu, Nisile Kakongoma, Wen-sheng Hu, Yan-zhen Zhang, Nan-nan Yang, Wen Zhang, Ai-fen Mao, Yi Liang, Zhi-fen Zhang   +8 more
doaj   +1 more source

11q13.3q13.4 deletion plus 9q21.13q21.33 duplication in an affected girl arising from a familial four‐way balanced chromosomal translocation

Molecular Genetics & Genomic Medicine, 2023
Background We describe a 13‐year‐old girl with a 11q13.3q13.4 deletion encompassing the SHANK2 gene and a 9q21.13q21.33 duplication. She presented with pre‐ and postnatal growth retardation, global developmental delay, severe language delay, cardiac ...
Qinxin Zhang, Yan Wang, Jing Zhou, Ran Zhou, An Liu, Lulu Meng, Xiuqing Ji, Ping Hu, Zhengfeng Xu   +8 more
doaj   +1 more source

A Qualitative Study of an Integrated Maternity, Drugs and Social Care Service for Drug-using Women [PDF]

, 2006
Background: The care of drug-using pregnant women is a growing health and social care concern in many countries. A specialist clinic was established offering multidisciplinary care and advice to pregnant drug users in and around Aberdeen (UK) in 1997 ...
Hall, Jenny, van Teijlingen Edwin R, Hall Jennifer L, van Teijlingen, Edwin, Jennifer L Hall, van Teijlingen, Edwin R, Edwin R van Teijlingen, Hall, Jennifer L   +7 more
core   +2 more sources

Case Report: The third-generation sequencing confirmed a novel 7.2 Kb deletion at β-globin gene in a patient with rare β-thalassemia

Frontiers in Genetics, 2022
Background: Thalassemia was the most common monogenic diseases worldwide, which was caused by mutations, deletions or duplications in human globin genes which disturbed the synthesis balance between α- and β-globin chains of hemoglobin.
Guoxing Zhong, Zeyan Zhong, Zhiyang Guan, Dina Chen, Zhiyong Wu, Kunxiang Yang, Dan Chen, Yinyin Liu, Ruofan Xu, Jianhong Chen   +9 more
doaj   +1 more source

Challenges of maternal and prenatal care in Nigeria [PDF]

, 2019
Background and aim: Evidence in the literature indicates that maternal health care by a skilled birth attendant is one of the key strategies for maternal survival.
Matheson, David, Ekpenyong, Mandu Stephen, Bond, Carol   +2 more
core   +1 more source