International Journal of Dermatology, EarlyView.ABSTRACT Gonorrhea, a common sexually transmitted infection caused by Neisseria gonorrhoeae, represents an escalating global public health threat due to antimicrobial resistance. The current review explores diverse approaches around the globe to gonorrhea management across various settings, with a focus on diagnostic strategies, treatment practices ...
Andrei Tanasov +2 more
wiley +1 more source
Associations of In Utero Exposure to Racial Violence and Reproductive Development: The Bogalusa Heart Study. [PDF]
Am J Hum BiolSantos MP +4 more
europepmc +1 more source
Molecular Testing in Sickle Cell Disease: From Newborn Screening to Transfusion Care
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Sickle cell disease (SCD) is one of the most frequent monogenic diseases worldwide and a highly heterogeneous and complex disease. SCD care carries several challenges. This includes early and accurate diagnosis as well as optimal red blood cell transfusion matching in this population carrying a high risk of alloimmunization.
Thomas Pincez, Yves D. Pastore
wiley +1 more source
Preventing Differentiation Towards Primitive Macrophages in Stem Cells With Down Syndrome
Immunology, EarlyView.Decreased fetal brain macrophages were previously reported in Ts1Cje mice, a model of Down syndrome (DS). We confirmed the reduction in primitive macrophages, brain macrophage precursors, using Ts1Cje‐derived mouse embryonic stem cells (Ts1Cje‐mESCs) and human induced pluripotent stem cells with trisomy 21 (Tri21‐hiPSCs), with in vivo validation ...
Koki Harada +9 more
wiley +1 more source
Journal of Advanced Nursing, EarlyView.ABSTRACT Aim To explore the perspectives and experiences of maternity care providers regarding obstetric violence across low‐, middle‐, and high‐income countries. Design An integrative review of the literature. Methods A systematic literature search in CINAHL, Medline (via Ovid), SCOPUS, and the Cochrane Library was conducted from 2014 to 2024. Further
Emma C. Collins +3 more
wiley +1 more source
Prenatal stress and neuroendocrine pathways framing attention-deficit/hyperactivity disorder as a functionally based neurodevelopmental disorder: a narrative review. [PDF]
J Yeungnam Med SciJung SC.
europepmc +1 more source
Distinct DNA methylation in mother-infant dyads exposed to PM2.5 in pregnancy. [PDF]
Clin EpigeneticsKlibaner-Schiff E +8 more
europepmc +1 more source
Annual Research Review: Early conduct problems – precursors, outcomes, and etiology
Journal of Child Psychology and Psychiatry, EarlyView.During the toddler and preschool period, nearly all children engage in some level of aggression, defiance, stealing, and temper tantrums. While the frequency and intensity of these behaviors tends to decrease across early childhood, a subset of children engage in these conduct problem behaviors at a higher intensity early in life and/or do not desist ...
Luke W. Hyde +2 more
wiley +1 more source
Translational implications of circadian activity alterations in an experimental model of late-onset depression induced by prenatal excess of glucocorticoids. [PDF]
Front Behav NeurosciSpulber S +4 more
europepmc +1 more source
Practitioner Review: Infant mental health meets cell and molecular biology – a look to the future
Journal of Child Psychology and Psychiatry, EarlyView.Background A major research effort in the past two decades has begun to illuminate how experience ‘gets under the skin’ – that is – the cellular and molecular processes that are associated with adversity and resilience. Methods We selectively review three areas of this research: epigenetics, especially DNA methylation, telomere length, and inflammatory
Charles H. Zeanah +3 more
wiley +1 more source