Results 91 to 100 of about 63,552 (287)

Maternal prenatal stress and placental gene expression of NR3C1 and HSD11B2: The effects of maternal ethnicity [PDF]

Psychoneuroendocrinology, 2018
BACKGROUND: Prenatal stress is associated with altered fetal and infant development. Previous studies have suggested that these effects may be mediated in part via altered functioning of placental enzymes and receptors involved in the HPA-axis, including the glucocorticoid receptor (NR3C1) and HSD11B2, the enzyme which metabolises cortisol.
Capron, L, Ramchandani, P, Glover, V
openaire   +5 more sources

Children's stress regulation mediates the association between prenatal maternal mood and child executive functions for boys, but not girls [PDF]

, 2018
Prenatal exposure to maternal mood disturbances shapes children's cognitive development reflected in the critical construct of executive functions (EFs). Little is known, however, about underlying mechanisms.
Oberlander, Tim F., Weinberg, Joanne, Grunau, Ruth E., Hookenson, Kaia, Brain, Ursula, Devlin, Angela M., Neuenschwander, Regula, Diamond, Adele   +7 more
core   +1 more source

On the importance of including both sexes in animal studies – insights from home‐cage monitoring

Biological Reviews, EarlyView.
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater, Adam Dušek, Aleksandra Bartelik, Silvia Mandillo, Elisabetta Golini, Mara Rigamonti, Rasneer Sonia Bains, Hamish Forrest, Marion Rivalan, Melissa Long, Anna Kiryk, Lars Lewejohann, Nuno Henrique Franco   +12 more
wiley   +1 more source

Sexual aggression and prenatal stress lead to poor maternal care and aggressive behaviour in male Wistar rat offspring

IBRO Neuroscience Reports
Sexual aggression and prenatal stress can exert profound intergenerational effects, disrupting maternal care and enhancing aggression in offspring via alterations to the hypothalamic–pituitary–adrenal (HPA) axis and related neurochemical systems.
Elvis Mbiydzenyuy Ngala, Sian Megan Joanna Hemmings, Jacqueline Samantha Womersley, Thando W. Shabangu, Lihle-Appiah Qulu   +4 more
doaj   +1 more source

Maternal prenatal stress and infant regulatory capacity in Mexican Americans [PDF]

Infant Behavior and Development, 2014
The early postpartum period lays important groundwork for later self-regulation as infants' dispositional traits interact with caregivers' co-regulatory behaviors to produce the earliest forms of self-regulation. Although emerging literature suggests that fetal exposure to maternal stress may be integral in determining child self-regulatory capacity ...
Betty Lin, Keith A. Crnic, Linda J. Luecken, Nancy A. Gonzales   +3 more
openaire   +2 more sources

A White Paper on Advancing Long‐Acting Therapeutics for Maternal and Pediatric Health by Bridging Gaps in Clinical Research, Access and Regulation

Clinical Pharmacology &Therapeutics, EarlyView.
As use cases for long‐acting therapeutics expand across clinical indications, there is a critical need to ensure the inclusion of women who are pregnant or breastfeeding, infants and children—populations with a historical gap in the availability of interventions already approved for use in adults.
Moherndran Archary, Robert Bies, Osei Boateng, Rachel Daley, Pierre Gashema, Mili Karina, Emily Njuguna, Sharon Nachman, Nathaniel Nkrumah, Carolyne Odula, Andrew Owen, Ethel D. Weld, Prajith Venkatasubramanian, Adeniyi Olagunju, on behalf of the Community of Practice for Long‐acting Therapeutics for Maternal and Paediatric Health, Rana Abutaima, Dorothy Akongo, Abdulnaser Alsharaa, Moherndran Archary, Shakir Atoyebi, Benoit Bestgen, Robert Bies, Osei Boateng, Andrew Butler, Edmund Capparelli, Rachel Daley, Layla Davies, Joelle Dountio, Henry Enzama, Pierre Gashema, Katila George, Dan Hawcutt, Rene Holm, Patrick Gad Iradukunda, Elodie Jambert, Mili Karina, Linda Lewis, Grace Miheso, Sebastien Morin, Andrew Morrison, Sharon Nachman, Shadia Nakalema, Emily Njunga, Nathaniel Nkrumah, Carolyne Odula‐Obonyo, Brenda Okware, Adeniyi Olagunju, Andrew Owen, Martina Penazzato, Natella Rakhmanina, Mphako Brighton Ratlabyana, Rachel Scott, Kimberly Struble, Andre‐Marie Tchouatieu, Catherine Unsworth, Prajith Venkatasubramanian, Catriona Waitt, Ethel Weld, Janine Winterbottom, Leena Zino   +59 more
wiley   +1 more source

Reducing Exposure Before Birth: An Interrupted Time Series Study of Prenatal Exposure to Fetotoxic Medications Under Risk Management Plans in Canada

Clinical Pharmacology &Therapeutics, EarlyView.
Canada's 2009 risk management plan (RMP) framework has not been evaluated for prenatal exposure impact. Conversely, widely used drugs such as nonsteroidal anti‐inflammatory drugs (NSAIDs) lack RMPs. We assessed first‐trimester exposure to RMP‐regulated medications following regulatory interventions and to NSAIDs following safety publications.
Nahiyan Saiyara Khan, Odile Sheehy, Lisiane Freitas Leal, Vanina Tchuente, Anick Bérard   +4 more
wiley   +1 more source

Prenatal maternal salivary hormones and timing of tooth eruption in early childhood: a prospective birth cohort study

Frontiers in Oral Health
BackgroundAlthough the mechanisms underlying tooth eruption are not fully understood, the prenatal maternal milieu, particularly stress exposures, appears to play an important role in dental development.
Ying Meng, Ruqian Yang, Nora Alomeir, Thomas G. O’Connor, Jerod M. Rasmussen, Felicitas B. Bidlack, Jin Xiao   +6 more
doaj   +1 more source

Maternal stress during pregnancy alters fetal cortico-cerebellar connectivity in utero and increases child sleep problems after birth

Scientific Reports, 2021
Child sleep disorders are increasingly prevalent and understanding early predictors of sleep problems, starting in utero, may meaningfully guide future prevention efforts.
Marion I. van den Heuvel, Jasmine L. Hect, Benjamin L. Smarr, Tamara Qawasmeh, Lance J. Kriegsfeld, Jeanne Barcelona, Kowsar E. Hijazi, Moriah E. Thomason   +7 more
doaj   +1 more source

Meta-Analysis of the Effect of Prenatal Stress on the Premature Birth [PDF]

, 2020
Background: Premature birth is a major global public health problem, especially in developing countries. One of the causes of this incident is exposure to psychological stress experienced during pregnancy. This study aims to estimate the magnitude of the
Prasetya, Hanung, Murti, Bhisma, Faujiah, Irfa Nur   +2 more
core