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Prenatal stress and risk for autism [PDF]
Neuroscience and Biobehavioral Reviews, 2008 This paper reviews several converging lines of research that suggest that prenatal exposure to environmental stress may increase risk for Autistic Disorder (AD). We first discuss studies finding that prenatal exposure to stressful life events is associated with significantly increased risk of AD, as well as other disorders, such as schizophrenia and ...
Kerim Munir +2 more
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Prenatal stress and epigenetics
Neuroscience and Biobehavioral Reviews, 2020In utero exposure to environmental stress in both animals and humans could result in long-term epigenome alterations which further lead to consequences for adaptation and development in the offspring. Epigenetics, especially DNA methylation, is considered one of the most widely studied and well-characterized mechanisms involved in the long-lasting ...
Susanne R De Rooij +2 more
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Prenatal stress, fetal imprinting and immunity
Brain, Behavior, and Immunity, 2008A comprehensive number of epidemiological and animal studies suggests that prenatal and early life events are important determinants for disorders later in life. Among them, prenatal stress (i.e. stress experienced by the pregnant mother with impact on the fetal ontogeny) has programming effects on the hypothalamic-pituitary-adrenocortical axis, brain ...
E Merlot, Winfried Otten
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Prenatal stress and brain development
Brain Research Reviews, 2010Prenatal stress (PS) has been linked to abnormal cognitive, behavioral and psychosocial outcomes in both animals and humans. Animal studies have clearly demonstrated PS effects on the offspring's brain, however, while it has been speculated that PS most likely affects the brains of exposed human fetuses as well, no study has to date examined this ...
Charil, Arnaud +3 more
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Prenatal stress and the programming of the HPA axis
Neuroscience and Biobehavioral Reviews, 2010There are several independent prospective studies showing that a wide variety of forms of prenatal stress can have long-term effects on the behavioural and cognitive outcome for the child. Animal studies have shown that prenatal stress, as well as affecting behaviour, can also reprogram the function of the HPA axis in the offspring.
Vivette Glover +2 more
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Prenatal stress attenuates ulceration in the activity stress paradigm
Physiology & Behavior, 1995In the present study, 28 pregnant rats were subjected to either light-restraint stress or no manipulation for days 14-21 of the gestational period. At approx. 50 days of age, both male (n = 16) and female (n = 16) prenatally stressed (PS) and control offspring were subjected to the activity stress (AS) paradigm. During this subsequent stress experience,
K G, Lambert +5 more
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Prenatal stress and childhood psychopathology
Child Psychiatry & Human Development, 1991The documentation of levels of prenatal maternal stress and anxiety of four populations of severely emotionally disturbed children and adolescents was retrospectively reviewed to examine their relationship to the later development of childhood psychopathology.
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Alteration of the effects of caffeine by prenatal stress
Pharmacology Biochemistry and Behavior, 1989We examined the effect of prenatal stress exposure on sensitivity to caffeine using behavioral and physiological measures. Pregnant rats were handled 5 minutes daily from the 14th to 21st day of gestation. Male offspring were tested when 60 days of age in a modified open field apparatus 30 and 90 minutes after injection with caffeine (0, 10, 30 mg/kg).
L A, Pohorecky +3 more
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2019
Mothers’ experiences during pregnancy have important effects on children’s developmental outcomes. A significant body of literature suggests that effects of the maternal social environment can become biologically embedded to affect the health of her foetus, with mothers’ stress during pregnancy contributing to a range of child outcomes across ...
Michael Ungar +4 more
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Mothers’ experiences during pregnancy have important effects on children’s developmental outcomes. A significant body of literature suggests that effects of the maternal social environment can become biologically embedded to affect the health of her foetus, with mothers’ stress during pregnancy contributing to a range of child outcomes across ...
Michael Ungar +4 more
openaire +1 more source