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Neuroepigenetics of Prenatal Psychological Stress

2018
Life does not start at birth but at conception. What a person experiences during the first 9 months of life in the intrauterine environment will have lasting effects on health and disease later in life. Psychological stress in pregnant women has a number of potential negative consequences for the physical and psychological function of their children ...
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Cortisol: The Culprit Prenatal Stress Variable

International Journal of Neuroscience, 2008
Elevated prenatal cortisol has been associated with several negative conditions including aborted fetuses, excessive fetal activity, delayed fetal growth and development, prematurity and low birthweight, attention and temperament problems in infancy, externalizing problems in childhood, and psychopathology and chronic illness in adulthood.
Tiffany, Field, Miguel, Diego
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Prenatal Stress, Glucocorticoids and the Programming of the Brain

Journal of Neuroendocrinology, 2001
AbstractA large body of human epidemiological data, as well as experimental studies, suggest that environmental factors operating early in life potently affect developing systems, permanently altering structure and function throughout life. This process with its persistent organizational effects has been called ‘programming’.
L A, Welberg, J R, Seckl
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Glucocorticoids, prenatal stress and the programming of disease

Hormones and Behavior, 2011
An adverse foetal environment is associated with increased risk of cardiovascular, metabolic, neuroendocrine and psychological disorders in adulthood. Exposure to stress and its glucocorticoid hormone mediators may underpin this association. In humans and in animal models, prenatal stress, excess exogenous glucocorticoids or inhibition of 11β ...
Anjanette, Harris, Jonathan, Seckl
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The prenatal stress syndrome: Current status

Psychoneuroendocrinology, 1984
Exposure of female rats to stressors during the last week of pregnancy results in a selective feminization and demasculinization of adult sexual behaviors in the male offspring. No behavioral abnormalities are detectable in the female offspring, and reproductive morphological structures appear normal in both sexes.
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Prenatal Stress and Risk of Spontaneous Abortion

Psychosomatic Medicine, 2013
The aim of this study was to evaluate the association between exposure to life-threatening rocket attacks and spontaneous abortions (SAs).This is a historical cohort study comparing 1345 pregnancies of female residents of a town exposed to rocket attacks with 2143 pregnancies of female residents of an unexposed town.
Tamar, Wainstock   +4 more
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Effects of prenatal stress on the fetal calf

Domestic Animal Endocrinology, 1997
Twelve pregnant Brahman cows were randomly assigned to one of two treatment groups: 1) transported in a stock trailer for 24.2 km, unloaded at a second farm and penned for 1 hr, and then returned to the original farm (TRANS, n = 6); or 2) walked through the handling facilities (SHAM, n = 6).
D C, Lay   +8 more
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Stress and anxiety associated with prenatal diagnosis

Best Practice & Research Clinical Obstetrics & Gynaecology, 2007
Prior to any specific prenatal diagnostic procedure, the pregnant woman should be counselled about the indications for the procedure and how the diagnosis would inform care. In addition, the risks and limitations should be clearly spelt out. The availability of non-invasive prenatal diagnostic procedures such as sonography appears to have led to a ...
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Handedness, prenatal stress and pregnancy complications

Neuropsychologia, 1988
Two hundred and ninety children aged 2 yr were assessed for laterality on a number of preference and dexterity tasks. The mothers were interviewed about their child's pre- and perinatal history. Information was also obtained from hospital records about pregnancy and delivery stress and complications.
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Protein peroxidation in the plasma of prenatally stressed rats

Bulletin of Experimental Biology and Medicine, 2004
We studied the effect of prenatal stress on protein peroxidation in the plasma of rats during postnatal ontogeny. Oxidative destruction of proteins in prenatally stressed rats differed from that in control animals. These differences were most pronounced in postnatal ontogeny, i.e. during the development and maturation of CNS.
A V, V'yushina   +2 more
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