Results 141 to 150 of about 5,393,793 (388)

Chaperone‐Mediated Autophagic Degradation of USP9X in Macrophages Exacerbates Postmyocardial Infarction Inflammation and Cardiac Dysfunction

open access: yesAdvanced Science, EarlyView.
This study demonstrates that inflammatory stimuli induce the acetylation‐triggered, chaperone‐mediated autophagic degradation of ubiquitin‐specific peptidase 9 X‐linked (USP9X) in macrophages. USP9X acts as a macrophage “inflammation switch” after myocardial infarction (MI). USP9X loss destabilizes tumor necrosis factor receptor‐associated factor (TRAF)
Biqing Wang   +7 more
wiley   +1 more source

Patient Satisfaction from Pre and Postoperative Nursing Care in Hospitals Affiliated to Babol University of Medical Sciences

open access: yesPreventive Care in Nursing and Midwifery Journal, 2013
Background and Objectives: Patient satisfaction is an important concept and priority in health system. The aim of this study was to assess patientschr('39') satisfaction from nursing care in hospitals of Iran University of Medical Sciences. Materials and
Yosof Mortazavi   +4 more
doaj  

Body mass index and lower limb diameters in total knee arthroplasty outcomes and surgical planning

open access: yesRheumatology
Introduction Total knee arthroplasty (TKA) is a commonly performed surgery that can successfully treat end-stage osteoarthritis (OA). Obesity is a known risk factor for OA and its progression, but its impact on postoperative satisfaction and implant ...
Marcin Łapiński   +7 more
doaj   +1 more source

Redox‐Programmed Activation of a Dual‐Modal Probe for High‐Fidelity Tumor Delineation and Image‐Guided Surgery

open access: yesAdvanced Science, EarlyView.
This study presents a glutathione (GSH)‐activatable dual‐modality probe (GAP9) with a redox‐tuned activation window for precise tumor detection. It remains quenched (“OFF”) in normal tissue yet activates specifically in tumors for T1‐weighted magnetic resonance imaging (MRI) preoperative mapping and near‐infrared II (NIR‐II) fluorescence intraoperative
Haohao Yan   +4 more
wiley   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu   +7 more
wiley   +1 more source

Preoperative assessment of adults undergoing elective noncardiac surgery

open access: yesEuropean Journal of Anaesthesiology
BACKGROUND When considering whether a patient is fit for surgery, a comprehensive patient assessment represents the first step for an anaesthetist to evaluate the risks associated with the procedure and the patient's underlying diseases, and to optimise (
Massimo Lamperti   +16 more
semanticscholar   +1 more source

Photoacoustic Microscopy for Multiscale Biological System Visualization and Clinical Translation

open access: yesAdvanced Science, EarlyView.
Photoacoustic microscopy (PAM) is a powerful biomedical imaging tool renowned for its non‐invasiveness and high resolution. This review synthesizes recent technological advances and highlights their broad applications from cellular and organ‐level to whole‐animal imaging.
Tingting Wang   +3 more
wiley   +1 more source

Preoperative Care Assessment of Need Scores Are Associated With Postoperative Mortality and Length of Stay in Veterans Undergoing Knee Replacement. [PDF]

open access: yesFed Pract, 2021
Kuo M   +7 more
europepmc   +1 more source

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