Results 111 to 120 of about 3,730,080 (218)

Rabdosia rubescens Inhibits CYP7A1 Expression and Induces Autophagy to Reduce Alcohol-Induced Liver Damage in Mice

Canadian Journal of Gastroenterology and Hepatology
Xi Zou, Wei Chen, Yidan Shao, Tingting Shi, Yunling Ke   +4 more
doaj   +1 more source

Current Status of Shared Decision-Making in Intraocular Lens Selection for Cataract Surgery: A Cross-Sectional Study

Patient Preference and Adherence
Jingyao Dai,1 Yiting Hua,1 Yijie Chen,1 Jiali Huang,1 Xiaoxian Zhang,1 Yiwen Sun,1 Chen Chen,1 Yanyan Chen,2 Kaijing Zhou2 1School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China; 2National ...
Dai J, Hua Y, Chen Y, Huang J, Zhang X, Sun Y, Chen C, Chen Y, Zhou K   +8 more
doaj  

Examining educational leadership preparation and development programmes in the Gulf region: a comparative study of Bahrain, Kuwait and Qatar

London Review of Education
This article is based on a comparative study that addresses signature pedagogies in leadership preparation and development policies and programmes in Kuwait, Qatar and Bahrain.
doaj   +2 more sources

Peroneus Longus Autograft Harvest and Preparation for Anterior Cruciate Ligament Reconstruction. [PDF]

Arthrosc Tech
Park M, Bouwkamp N, Riggs T, Hamilton K, Menge T.   +4 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Preparation for bias, racial-ethnic socialization competency, and Latinx adolescent mental health. [PDF]

J Res Adolesc
Gomez Alvarado CJ, Kiang L, Anderson RE, Stevenson HC, Christophe NK, Jones SCT, Livas G.   +6 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Use of glucagon-like peptide-1 receptor agonists is associated with inadequate bowel preparation for colonoscopy in patients with diabetes. [PDF]

J Diabetes Investig
Ogawa O.
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Preparation of B. Braun Easypump^® II elastomeric devices with Chemfort^™ closed system transfer devices (CSTDs) in uncontrolled environments. [PDF]

JAC Antimicrob Resist
Knowles L, Jenkins A.
europepmc   +1 more source