Results 291 to 300 of about 8,738,312 (332)

Which Surgical Hand Preparation Method Is More Effective? A Comparative Study of Hand Rub and Hand Scrub. [PDF]

Nurs Rep
Olivia C, Ibrahim K, Kurniawan T.
europepmc   +1 more source

Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3

FEBS Open Bio, EarlyView.
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno, Aki Terasaki, Yuiko Imai, Yuri Kimura, Yuna Kojima, Misa Irie, Koya Odaira, Mina Noura, Shuichi Okamoto, Takahiko Yasuda, Shinobu Tsuzuki, Hitoshi Kiyoi, Fumihiko Hayakawa   +12 more
wiley   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

FEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr, Michael Fauler, Thomas Zimmer, Bettina Jungwirth, Hubert Schrezenmeier, David Alexander Christian Messerer   +5 more
wiley   +1 more source

Prepare to persist

Protoplasma
openaire   +4 more sources

Advances in the extracellular vesicles treatment of alopecia. [PDF]

Ann Med
Wu X, Tang S.
europepmc   +1 more source

The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions

FEBS Open Bio, EarlyView.
Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh, Esther Lee, Soo‐A Kim   +2 more
wiley   +1 more source

Intravenous medication administration practices: insights into knowledge, attitude, and behavior of intensive care unit (ICU) nurses in Pakistan. [PDF]

BMC Nurs
Ahmad T, Sitaruno S, Pattharachayakul S, Kiddeer M, Khan SA.   +4 more
europepmc   +1 more source

Advancing the pathway to allogeneic hematopoietic stem cell transplantation through a physician-nurse coordinator system in patients with acute leukemia. [PDF]

Sci Rep
Auepisit C, Owattanapanich W, Kungwankiattichai S, Kunacheewa C, Atakulreka S, Kulchutisin K, Donsakul N.   +6 more
europepmc   +1 more source

Influence of engine driven nickel titanium metallurgy and preparation kinematics on apical sensing during apex locator integrated instrumentation. [PDF]

BMC Oral Health
Özdemir O, Kaşıkçı S, Özbek SK, Gündoğar M.   +3 more
europepmc   +1 more source