Results 51 to 60 of about 3,597,688 (265)

Simultaneous Determination of Three Effective Components in Different Compatibility Proportion of the Couple of Sophora flavescens-Fructus Ligustri lucidi by HPLC

MATEC Web of Conferences, 2018
Sophora flavescens - Ligustrum lucidum has the effect of increasing the anti-cancer effect of white blood cells and treating liver fibrosis. In order to determine the optimal compatibility ratio of this drug pair, the rationality of the drug pairs in ...
Chu Shuhan, Zhang Hongxu, Ding Lixin
doaj   +1 more source

Improvement of Sickle Cell Disease Care Mitigates the Healthcare Utilization Induced by Increased Prevalence: Experience of a Tertiary Pediatric Center

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) has undergone major changes in the last decades. Its prevalence has been steadily increasing and numerous advances have been made in the management of the disease. However, the effect in real‐life setting of these major changes is unknown, particularly in a Canadian environment. Procedure We aimed to assess
Maude Cigna, Alexia Muresan, Estelle Lecluze, Karine Leduc, Nathalie Fournier, Maria Tamer, Jean‐François Delisle, Jeremi Charbonneau, Annie Viau, Jessica Darilus, Marie‐Joëlle Doré‐Bergeron, Valérie Arsenault, Evelyne Doyon‐Trottier, Stéphanie Forte, Nancy Robitaille, Yves Pastore, Thomas Pincez   +16 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Extracellular Vesicles for Therapeutic Applications: A Translational Framework Integrating Sources, Administration Routes, Indications, Quality Control, and Regulatory Systems

International Journal of Nanomedicine
Fen Zhang,1,* Lan Xing,1,* Wanglong Chu,1 Qingfang Wang,1 Haojie Sun,1 Yajun Liu,1 Gang An,2 Xiao Liang1 1Cell Preparation Center, Shenzhen Beike Biotechnology Co., Ltd., Shenzhen, Guangdong, People’s Republic of China; 2Fujian Branch ...
Zhang F, Xing L, Chu W, Wang Q, Sun H, Liu Y, An G, Liang X   +7 more
doaj  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Cryopreserved Umbilical Cord Mesenchymal Stem Cells Show Comparable Effects to Un-Cryopreserved Cells in Treating Osteoarthritis

Cell Transplantation
Non-cryo and hypothermic preservations are two available options for short-term storage of living cells. For long-term cell storage, cryopreservation is an essential procedure as it prolongs the storage time, allowing for the transport and testing of ...
Bo Yan, Huixin Chen, Li Yan, Qiang Yuan, Le Guo   +4 more
doaj   +1 more source

Effects of Fluoroquinolone Antibiotics on Denitrification in Groundwater: A Review

Yankuang ceshi
Microbially mediated denitrification is essential for nitrate removal in groundwater. Fluoroquinolones (FQs) pollution, mainly from reclaimed water and livestock farming, often co-occurs with nitrate and may influence denitrification. Recent studies have
Hua ZOU, Jiangtao HE, Fei LIU, Qiwen XIA, Yanjia CHU   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Andrographolide Inhibits the NF-κB Signaling Pathway and Alleviates High-Fat Diet-Induced Hepatic Inflammation in a Mouse Model of Nonalcoholic Fatty Liver Disease

Natural Product Communications
Background High-fat diet (HFD)-induced nonalcoholic fatty liver disease (NAFLD) is a key link between several medical conditions and is becoming a major health concern affecting thousands of people globally.
Weiwen Hu, Yilin Chen, Wenhong Tan, Yirong Wang, Die Huang, Hao Yuan   +5 more
doaj   +1 more source