Results 81 to 90 of about 4,526,308 (312)

The literacy preparation in Turkish preschool education.

, 2022
The purpose of this study is to reveal the views and recommendations of the preschool and primary school teachers on the literacy preparation in Turkish preschool education. The study is designed as phenomenological research.
Sabri Sidekli, Semra Tican Başaran
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Cryopreserved Umbilical Cord Mesenchymal Stem Cells Show Comparable Effects to Un-Cryopreserved Cells in Treating Osteoarthritis

Cell Transplantation
Non-cryo and hypothermic preservations are two available options for short-term storage of living cells. For long-term cell storage, cryopreservation is an essential procedure as it prolongs the storage time, allowing for the transport and testing of ...
Bo Yan, Huixin Chen, Li Yan, Qiang Yuan, Le Guo   +4 more
doaj   +1 more source

Effects of Fluoroquinolone Antibiotics on Denitrification in Groundwater: A Review

Yankuang ceshi
Microbially mediated denitrification is essential for nitrate removal in groundwater. Fluoroquinolones (FQs) pollution, mainly from reclaimed water and livestock farming, often co-occurs with nitrate and may influence denitrification. Recent studies have
Hua ZOU, Jiangtao HE, Fei LIU, Qiwen XIA, Yanjia CHU   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Polylactide microcapsules and films: preparation and properties

, 2009
This thesis aims at preparation of hollow polylactide (PLA) microcapsules for use as ultrasound contrast agents with controlled size, structure and mechanical and thermal properties.
Sawalha, H.I.M.
core  

Andrographolide Inhibits the NF-κB Signaling Pathway and Alleviates High-Fat Diet-Induced Hepatic Inflammation in a Mouse Model of Nonalcoholic Fatty Liver Disease

Natural Product Communications
Background High-fat diet (HFD)-induced nonalcoholic fatty liver disease (NAFLD) is a key link between several medical conditions and is becoming a major health concern affecting thousands of people globally.
Weiwen Hu, Yilin Chen, Wenhong Tan, Yirong Wang, Die Huang, Hao Yuan   +5 more
doaj   +1 more source

The lottery preparation

Annals of Pure and Applied Logic, 2000
The lottery preparation, a new general kind of Laver preparation, works uniformly with supercompact cardinals, strongly compact cardinals, strong cardinals, measurable cardinals, or what have you. And like the Laver preparation, the lottery preparation makes these cardinals indestructible by various kinds of further forcing.
openaire   +3 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source