Results 141 to 150 of about 21,340,911 (255)
A COMPLEX THREE-UNIT PARALLEL SYSTEM WITH PREPARATION TIME FOR REPAIR
South African Journal of Industrial Engineering, 2012 <p>ENGLISH ABSTRACT: It is reasonable to expect that preparation time is needed to ready a repair facility before a repair can be carried out. A three-unit system with a `preparation time’ for the repair facility is studied in this paper.
Y.A. Mwanga +2 more
doaj
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Integrated sample preparation devices and applications in proteome study
, 2011 Due to the complexity of proteomes, with the present strategies, it usually takes rather long time for the preparation, separation and identification of proteomic samples, no matter for qualitative or quantitative analysis.
张玉奎, 张丽华
core
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Progress on human-in-the-loop data preparation
大数据, 2019 With the rapid development of data analytics,data preparation has become a major bottleneck.The two essential challenges for data preparation on cost and time were analyzed.To address the challenges,the research progress on human-in-theloop data ...
Ju FAN, Yueguo CHEN, Xiaoyong DU
doaj
Molecular Oncology, EarlyView.Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Development of an In-House Assistant Application to Reduce Preparation Time of Preoperative Informed Consent Forms for Anesthesia. [PDF]
CureusTakekoshi M +4 more
europepmc +1 more source