Results 131 to 140 of about 17,634 (279)

Heat Stress Modulates WDR5‐Mediated H3K4me3 Modification to Induce Melanogenesis via Activating CX3CL1/CX3CR1 Axis

open access: yesAdvanced Science, Volume 13, Issue 7, 3 February 2026.
This study elucidates the mechanism by which heat stress regulates skin pigmentation: heat stress upregulates CX3CL1 through the MYC‐WDR5‐H3K4me3 axis, thereby activating the CX3CL1/CX3CR1‐JNK signaling pathway and ultimately promoting melanogenesis. These findings provide novel potential therapeutic targets for pigmentary skin disorders.
Yushan Zhang   +6 more
wiley   +1 more source

Megameatus intact prepuce with distal megalourethral dilatation: A case report and review of the literature

open access: yesIbom Medical Journal
Introduction: Megameatus Intact Prepuce is a rare and often under-recognised variant of distal hypospadias, as the normal-appearing foreskin may mask the underlying urethral abnormality.
Akpanudo EI   +5 more
doaj   +1 more source

What Is Your Diagnosis? Dermal Mass From the Left Forelimb of a Dog

open access: yes
Veterinary Clinical Pathology, EarlyView.
Heather D. McDavid   +3 more
wiley   +1 more source

One‐Step Coaxial 3D Printing of Pre‐Vascularized Skin Organoid Models with ADSC Microspheres for Enhanced Wound Healing

open access: yesAdvanced Science, Volume 13, Issue 9, 13 February 2026.
A multifunctional vascular bed platform is created using coaxial 3D printing, allowing the one‐step integration of organoid microspheres with perfusable vascular structures. This strategy enables rapid and functional vascularization of organoids to support tissue repair and vascularization, providing a scalable and translationally promising approach ...
Kunrui Wang   +10 more
wiley   +1 more source

SNODGRASS Procedure A Versatile Technique for Various Types of Hypospadias Repair [PDF]

open access: yes, 2013
There are about 156 operations described forhypospadias. The sheer number of proceduresindicates that no single procedure is standardfor hypospadias. We report our series of 20patients operated for hypospadias by Snodgrassprocedure. The technical details
Dhandore P. D.   +3 more
core  

Ventilator‐Induced Lung Injury: Mechanotransduction and Potential Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Mechanical ventilation (MV) is expected to undergo significant transformative advancements by 2050, with the emergence of personalized ventilation systems that promise to revolutionize respiratory care. However, the risk of ventilator‐induced lung injury (VILI) remains a significant concern at this stage and VILI still exists at that time.
He Ren   +4 more
wiley   +1 more source

Chemical dehydration‐induced ultrafast clearing method for human tissues

open access: yesVIEW, Volume 7, Issue 1, February 2026.
Three‐dimensional (3D) histology of human tissue through clearing has been hampered by the lengthy and intricate procedure. Here, a rapid and straightforward clearing protocol termed single‐step dehydration solvent‐based clearing (SSD) is proposed via a chemical dehydration strategy.
Yi Dai   +16 more
wiley   +1 more source

Non‐resectable extratesticular sustentacular cell tumour treated with palliative‐intent radiation and carboplatin chemotherapy in a dog

open access: yesVeterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract There is limited published information regarding the diagnosis and treatment of sustentacular cell neoplasia in dogs, and no data evaluating the use of radiation and chemotherapy for those tumours that are non‐resectable. This case report describes a 5‐year‐old, male, neutered German shepherd dog presented with a large, rapidly growing ...
Kathryn J. Jensen   +3 more
wiley   +1 more source

A Novel Human Cellular System for Studying Normal Aging and for Anti‐Aging Discovery

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
This study introduces a human cellular aging model using placental trophoblasts (hTSC‐STBs) that mimics key aging features like senescence and genomic instability. It aligns with human tissue aging and responds to anti‐aging treatments, offering a scalable platform to screen potential therapies and bridge lab findings to clinical applications ...
Zhen Feng   +14 more
wiley   +1 more source

A proposal for a shallow ontologization of WordNet [PDF]

open access: yes, 2005
En este artículo se presenta el trabajo que se está realizando para la llamada ontologización superficial de WordNet, una estructura orientada a superar muchos de los problemas estructurales de la popular base de conocimiento léxico.
Atserias Batalla, Jordi   +2 more
core  

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