Results 131 to 140 of about 20,128 (273)

Substrate‐Dependent Crosslinking by the Cytochrome P450 From Aminopyruvatide Biosynthesis

Angewandte Chemie, EarlyView.
Substitutions in the aminopyruvatide precursor peptide altered the C─C linkage formed from a YLY motif by the P450 ApyO to a N─C linkage in a WLY motif. Moreover, constitutional isomers crosslinked by C─C and C─O linkages were formed from YYY or YWY motifs. ABSTRACT Cytochrome P450s catalyze an array of reactions including crosslinking of aromatic side
Chandrashekhar Padhi, Dinh T. Nguyen, Lingyang Zhu, Lide Cha, Jesse W. Wald, Douglas A. Mitchell, Wilfred A. van der Donk   +6 more
wiley   +2 more sources

Langues officielles versus droits linguistiques : l’un exclut-il l’autre ?

Droit et Cultures, 2012
Several countries take for granted the fact that the choice of an official language is a State exclusive prerogative. This was confirmed by both the European Court of Human Rights and the U.N. Human Rights Committee on several occasions.
Fernand de Varennes
doaj  

Sustainable Access to N‐Heterocycles: One‐Pot Cascade Synthesis of Pyrroles From Bio‐Derived Furans

Angewandte Chemie, EarlyView.
Highly dispersed platinum (Pt) clusters on Brønsted acid‐rich HY zeolite enable a one‐pot cascade conversion of bio‐derived furans and nitroarenes into pyrroles. Highly dispersed Pt sites ensure selective nitro hydrogenation, while Pt nanoparticles promote undesired over‐hydrogenation.
Haifeng Qi, Germán López Robledo, Jianglin Duan, Yujing Ren, Kathrin Junge, Matthias Beller   +5 more
wiley   +2 more sources

A Modular Synthesis of C5‐Sulfenyl Thiazoles via an Intermolecular Pummerer Rearrangement: An Underexplored Scaffold for Medicinal Chemistry

Angewandte Chemie, EarlyView.
Modular access to underexplored C5‐sulfenyl thiazoles via an intermolecular Pummerer rearrangement is reported. The methodology exhibits a broad functional group tolerance enabling the seamless design of trisubstituted thiazole cores bearing a sulfur handle for further elaboration.
Joe L. Smy, Theo C. Webb, Barnaby W. Greenland, S. Mark Roe, John Spencer, Storm Hassell‐Hart   +5 more
wiley   +2 more sources

The good use of NSAID: when, why and how

Pathos, 2019
Non-steroidal anti-inflammatory drugs (NSAIDs) are the first line treatment of acute or recurrent pain and often remain the prerogative of the primary care physician if not the patient himself on self-administration.
Gianluca Conversa
doaj  

The Art of Medicine in Cancer Care: An Editor's Commentary on "Timeliness, Coordination, Clarity, and Kindness: Patients' Interpretations of Provider Actions as Indicators of Quality Cancer Care". [PDF]

Perm J
Holt GR.
europepmc   +1 more source

Establishing trust through clear communication and shared decision-making. [PDF]

CMAJ, 2023
Lamontagne F.
europepmc   +1 more source

Prometheus' fire and Brazilian universities: A decade of the quota law. [PDF]

Clinics (Sao Paulo)
Cunha LL, Ward LS.
europepmc   +1 more source

Précis of <i>Inducing Immunity? Justifying Immunization Policies in Times of Vaccine Hesitancy</i>  ¹. [PDF]

Public Health Ethics
Pierik R, Verweij M.
europepmc   +1 more source

Reply to the letter: autonomy and refusal of dialysis: ethical and legal reflections on the Brazilian Society of Nephrology Position Statement. [PDF]

J Bras Nefrol
Silva DRD, Polacchini FSG, Moura AF, Rodrigues CIS, Younes-Ibrahim M, Rocha E, Neiva MAOO, Rocha PT, Abreu PF, Moura-Neto JA.   +9 more
europepmc   +1 more source