Results 81 to 90 of about 29,420 (189)

Multimodal Locomotion of Soft Robots

Advanced Intelligent Systems, EarlyView.
This review comprehensively surveys recent advances in multimodal locomotion within soft robotics. Typical locomotion modes are summarized and categorized. Furthermore, the underlying mechanisms enabling multimodal locomotion are discussed and classified into three primary categories: active control‐based, reconfiguration‐based, and environment ...
Zihao Yuan, Huangwei Ji, Kai Huang, Feifei Chen, Guoying Gu   +4 more
wiley   +1 more source

Intratympanic dexamethasone microcrystals/lidocaine‐loaded PLGA non‐spherical microparticles for local drug delivery to the inner ear

Animal Models and Experimental Medicine, EarlyView.
Optimized lidocaine‐loaded PLGA non‐spherical particles (LPNMs) and dexamethasone microcrystals (DEX MCs) were prepared. They were then mixed in sodium hyaluronate solution to obtain a co‐delivery system, administrated in guinea pigs to evaluate the pharmacokinetics and biocompatibility of the system.
Dongcheng Wang, Xin Zhang, Zhen Wang, Cheng Ran, Jia Hao, Xiaobo Ma, Minghui Wang, Zhimin Zhou   +7 more
wiley   +1 more source

Beta Power Response After Levodopa Intake in Parkinson's Disease Patients With Chronic Sensing‐Enabled Deep Brain Stimulation

Annals of Neurology, EarlyView.
Objective In Parkinson's disease (PD), the power of beta oscillations (± 13–30 hertz [Hz]) from subthalamic nucleus (STN) local field potentials (LFPs) is associated with motor symptoms. Beta power can be used for adaptive deep brain stimulation (aDBS) algorithms based upon symptom fluctuations.
Martijn G.J. de Neeling, Bart J. Keulen, Mariëlle J. Stam, Deborah Hubers, Rob M.A. de Bie, Bernadette C.M. van Wijk, P. Rick Schuurman, Arthur W.G. Buijink, Martijn Beudel   +8 more
wiley   +1 more source

Dimer models and conformal structures

Communications on Pure and Applied Mathematics, EarlyView.
Abstract Dimer models have been the focus of intense research efforts over the last years. Our paper grew out of an effort to develop new methods to study minimizers or the asymptotic height functions of general dimer models and the geometry of their frozen boundaries.
Kari Astala, Erik Duse, István Prause, Xiao Zhong   +3 more
wiley   +1 more source

Ghost effect from Boltzmann theory

Communications on Pure and Applied Mathematics, EarlyView.
Abstract Taking place naturally in a gas subject to a given wall temperature distribution, the “ghost effect” exhibits a rare kinetic effect beyond the prediction of classical fluid theory and Fourier law in such a classical problem in physics. As the Knudsen number ε$\varepsilon$ goes to zero, the finite variation of temperature in the bulk is ...
Raffaele Esposito, Yan Guo, Rossana Marra, Lei Wu   +3 more
wiley   +1 more source

Pharmacokinetics and Bioequivalence of a Novel Extended‐Release Formulation of Methylphenidate Hydrochloride for Attention‐Deficit/Hyperactivity Disorder

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Extended‐release (ER) formulations of the stimulant methylphenidate are commonly used to treat attention‐deficit/hyperactivity disorder in both children and adults. Previous studies have shown that the clinical effectiveness of long‐acting methylphenidate formulations is closely tied to the drug's pharmacokinetic (PK) profile, highlighting the
Ann C. Childress, Ahmad AL‐Sabbagh, Jeffrey H. Newcorn   +2 more
wiley   +1 more source

The Pathway to Proof‐of‐Concept for BNC210, a Negative Allosteric Modulator of the Alpha‐7 Nicotinic Acetylcholine Receptor (nAChR), for Treatment of Psychiatric Disease

Clinical Pharmacology in Drug Development, EarlyView.
Abstract BNC210 is an investigational small molecule selective negative allosteric modulator of the alpha‐7 nicotinic acetylcholine receptor (α7 nAChR). It is an anxiolytic compound with a novel mechanism of action. In a series of Phase 1 clinical trials in healthy volunteers, psychometric test batteries showed that BNC210 did not cause attention ...
Paul Rolan, Elizabeth Doolin, Dharam Paul, Julia Crossman, Michael Odontiadis, Philippe Danjou, Mark Smith, Spyros Papapetropoulos   +7 more
wiley   +1 more source

Non-degeneracy of multi-bubbling solutions for prescribed scalar curvature problem via local Pohozaev identity

, 2022
Abstract This paper deals with the following nonlinear elliptic equation$$-\Delta u=Q(|y'|,y'')u^{\frac{N+2}{N-2}},\,\,u>0,\,\,\text{in}\R^N,\,\,u\inD^{1,2}(\R^{N}),$$where $(y',y'')\in \R^2\times\R^{N-2}$,$Q(|y'|,y'')$ is a bounded non-negative function in$\mathbb{R}^{2}\times \R^{N-2}$.
openaire   +1 more source

Growth Debunked for Investors

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Growth and degrowth have become key issues in the discourse on sustainability, and their quantification (growth/degrowth rates) has become integral to the limited number of indicators used to evaluate the ecological aspects of political and organizational decisions. This paper empirically examines the relevance of corporate growth and degrowth
Thi Le Hoa Vo, Gulliver Lux, Emmanuelle Fromont   +2 more
wiley   +1 more source

Damage modeling of CO2 injection well interfaces under coupled thermal, hydraulic and mechanical behavior

Deep Underground Science and Engineering, EarlyView.
This paper presents an investigation of CO2 injection well damage evolution considering different injection temperatures and the presence of a pre‐existing defect. The main outcome is that the accurate prediction of well leakage risk requires characteristics such as initial defects to be understood and represented in any modeling efforts. Abstract This
Lee J. Hosking, Xiangming Zhou
wiley   +1 more source