Results 31 to 40 of about 18,089 (204)

A survey exploring the knowledge and perceptions of senior medical students in Nepal toward generic medicines

SAGE Open Medicine, 2016
Background: The accurate knowledge of generic medicine issues among future prescribers will enhance the prescribing of cost-effective medicines. This study aimed to explore the knowledge and perception of senior medical students about the generic ...
Sudesh Gyawali, Mohamed Azmi Hassali, Archana Saha   +2 more
doaj   +1 more source

Evaluation of the quality of prescription orders in a tertiary health-care facility in Southeastern Nigeria

CHRISMED Journal of Health and Research, 2018
Background: Prescription orders serve as a source of communication linking the physician, patient, and pharmacist. However, inappropriate prescriptions may result in medication errors, thus may worsen clinical outcome and economic burden of the patient ...
Nneka Uchenna Igboeli, Chibueze Anosike, Onyinye Blessing Ukoha-Kalu, Ebere Emilia Ayogu   +3 more
doaj   +1 more source

Difference in rural and urban Medicare prescription pattern for Parkinson’s disease in Hawai‘i

Clinical Parkinsonism & Related Disorders, 2022
Background: Medical management of Parkinson’s Disease (PD) is becoming complex. Increasing evidence suggests that patients have better outcomes when they are managed by neurologists. However, access to neurologists can be limited in rural areas. Analysis
Michiko K. Bruno, Gina Watanabe, Fay Gao, Todd Seto, Kazuma Nakagawa, Connie Trinacty, Stacy Brown, Deborah A. Taira   +7 more
doaj   +1 more source

What are the ‘active ingredients’ of interventions targeting the public's engagement with antimicrobial resistance and how might they work? [PDF]

, 2018
Objectives. Changing public awareness of antimicrobial resistance (AMR) represents a global public health priority. A systematic review of interventions that targeted public AMR awareness and associated behaviour was previously conducted.
Davis, Mark, Flowers, Paul, Gozdzielewska, Lucyna, Langdridge, Darren, MacDonald, Jennifer, McParland, Joanna L., Price, Lesley, Smith, Fraser, Williams, Lynn, Young, Mairi   +9 more
core   +4 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Association between industry payments and prescribing costly medications: an observational study using open payments and medicare part D data

BMC Health Services Research, 2018
Background While many new medications may offer advantages over existing drugs, some newer drugs are reformulations of existing products that provide little innovation or incremental benefit while driving up drug costs.
Manvi Sharma, Aisha Vadhariya, Michael L. Johnson, Zachary A. Marcum, Holly M. Holmes   +4 more
doaj   +1 more source

Mind Your Meds: Safe Opioid Disposal Awareness [PDF]

, 2019
Driven by the effects of the opioid epidemic on friends, family members, students, and patients, members of the 2019 GEHLI Team “Mission Possible” are dedicated to bolstering educational awareness of safe leftover opioid disposal methods to decrease the ...
at Virginia Commonwealth University, The Grace E. Harris Leadership Institute, Davies, Mary Ann, Fox, Jenny, Johnson, Kenneth, Papenfuse, Jennifer, Schmitt, Michelle, Zhang, Shijun, Zoghby, Lori   +7 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Evaluation of Medicine-Use Pattern Using World Health Organization’s Core Drug-Use Indicators and Completeness of Prescription at University of Gondar Comprehensive Specialized Hospital, Gondar, Ethiopia: Cross-Sectional Study

Integrated Pharmacy Research and Practice, 2020
Kefyalew Ayalew Getahun,1 Adugnaw Sitotie Redia,2 Tezera Jemere Aragaw1 1Department of Pharmacology, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia; 2Department of Clinical Pharmacy, School of Pharmacy,
Ayalew Getahun K, Sitotie Redia A, Jemere Aragaw T   +2 more
doaj