Results 31 to 40 of about 7,607 (259)

Evaluation of Medicine-Use Pattern Using World Health Organization’s Core Drug-Use Indicators and Completeness of Prescription at University of Gondar Comprehensive Specialized Hospital, Gondar, Ethiopia: Cross-Sectional Study

open access: yesIntegrated Pharmacy Research and Practice, 2020
Kefyalew Ayalew Getahun,1 Adugnaw Sitotie Redia,2 Tezera Jemere Aragaw1 1Department of Pharmacology, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia; 2Department of Clinical Pharmacy, School of Pharmacy,
Ayalew Getahun K   +2 more
doaj  

Factors influencing the use of the “not for generic substitution” mention for prescriptions in primary care: a survey with general practitioners

open access: yesBMC Health Services Research, 2018
Background Generic drug substitution is a public health policy challenge with high economic potential. Generic drugs are generally cheaper than brand-name drugs. Drugs are a significant part of the total health expenditure, especially in ambulatory care.
Virgil Beauvais   +6 more
doaj   +1 more source

The adverse effects of brand-name drug prescribing

open access: yesCanadian Medical Association Journal, 2012
Prescribing drugs by their brand name appears to be more prevalent than ever.[1][1] Is this good practice? In particular, is it good for the prescribing physician? The answer to both questions has to be a resounding no. It is bad practice and it is bad for the physician’s mind and soul.
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Association of Industry Payments to Physicians With the Prescribing of Brand-name Statins in Massachusetts [PDF]

open access: yesJAMA Internal Medicine, 2016
Pharmaceutical industry payments to physicians may affect prescribing practices and increase costs if more expensive medications are prescribed.Determine the association between industry payments to physicians and the prescribing of brand-name as compared with generic statins for lowering cholesterol.Cross-sectional linkage of the Part D Medicare ...
James S, Yeh   +4 more
openaire   +2 more sources

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

CHOICE OF THE INITIAL TREATMENT FOR MILD TO MODERATE ARTERIAL HYPERTENSION IN MOSCOW PRIMARY PRACTICE

open access: yesРациональная фармакотерапия в кардиологии, 2015
Aim. To assess the choice of initial pharmacotherapy of uncomplicated mild to moderate arterial hypertension (HT) in Moscow primary care as well as to clear up the influence of regulatory measures on this choice.Material and methods.
S. V. Gatsura   +2 more
doaj   +3 more sources

The Role of Prescribing Generic (Non-proprietary) Drugs in the Prevalence of Therapeutic Inertia in Multiple Sclerosis Care

open access: yesFrontiers in Neurology, 2018
Importance: The prescription of generic (non-proprietary) compared to brand-name drugs is increasing worldwide. In many developing and emerging countries, generics companies market products at similar costs as brand-name competitors benefiting from more ...
Gustavo Saposnik   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy