Results 31 to 40 of about 7,607 (259)
Kefyalew Ayalew Getahun,1 Adugnaw Sitotie Redia,2 Tezera Jemere Aragaw1 1Department of Pharmacology, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia; 2Department of Clinical Pharmacy, School of Pharmacy,
Ayalew Getahun K +2 more
doaj
Background Generic drug substitution is a public health policy challenge with high economic potential. Generic drugs are generally cheaper than brand-name drugs. Drugs are a significant part of the total health expenditure, especially in ambulatory care.
Virgil Beauvais +6 more
doaj +1 more source
The adverse effects of brand-name drug prescribing
Prescribing drugs by their brand name appears to be more prevalent than ever.[1][1] Is this good practice? In particular, is it good for the prescribing physician? The answer to both questions has to be a resounding no. It is bad practice and it is bad for the physician’s mind and soul.
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Association of Industry Payments to Physicians With the Prescribing of Brand-name Statins in Massachusetts [PDF]
Pharmaceutical industry payments to physicians may affect prescribing practices and increase costs if more expensive medications are prescribed.Determine the association between industry payments to physicians and the prescribing of brand-name as compared with generic statins for lowering cholesterol.Cross-sectional linkage of the Part D Medicare ...
James S, Yeh +4 more
openaire +2 more sources
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Aim. To assess the choice of initial pharmacotherapy of uncomplicated mild to moderate arterial hypertension (HT) in Moscow primary care as well as to clear up the influence of regulatory measures on this choice.Material and methods.
S. V. Gatsura +2 more
doaj +3 more sources
Importance: The prescription of generic (non-proprietary) compared to brand-name drugs is increasing worldwide. In many developing and emerging countries, generics companies market products at similar costs as brand-name competitors benefiting from more ...
Gustavo Saposnik +8 more
doaj +1 more source

