Heroin Use and Prescription Drug Misuse in Kentucky [PDF]
The most recent Kentucky Health Issues Poll (KHIP) on heroin use and prescription drug misuse shows where our state's drug problems are hitting hardest. Northern Kentucky residents are twice as likely as other Kentucky residents to report knowing someone
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We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Out-of-Pocket Prescription Drug Expenditures and Public Prescription Drug Programs [PDF]
Canadian household prescription drug expenditures are studied using different years of the Statistics Canada Family Expenditure Survey. Master files are used, expanding the number of available years and permitting provincial rather than regional ...
Michael R. Veall +3 more
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Controlling Costs and Increasing Access to Prescription Drugs: State and Federal Solutions [PDF]
Spending on health care in the United States continues to increase rapidly, consuming a greater share of the total economy each year. Over the past decade, prescription drug spending has been the fastest growing component of health care expenditures both
Michael Sullivan, Rebecca Kavoussi
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Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
How the presentation of patient information and decision-support advisories influences opioid prescribing behavior: A simulation study [PDF]
ObjectiveThe United States faces an opioid crisis. Integrating prescription drug monitoring programs into electronic health records offers promise to improve opioid prescribing practices.
Hussain, Mustafa I +4 more
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Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin +2 more
wiley +1 more source
Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer +14 more
wiley +1 more source
Prescription History of Emergency Department Patients Prescribed Opioids
Introduction: To use Colorado’s prescription drug monitoring program (PDMP) to describe the recent opioid prescription history of patients discharged from our emergency department (ED) with a prescription for opioid pain medications.Methods ...
Jason A Hoppe +3 more
doaj +1 more source
What's Good for Washington: Fair Prescription Drug Pricing and the Biotechnology Industry [PDF]
The rising cost of prescription drugs is consuming an ever-larger portion of limited funds for basic health care and other important services in Washington state.
Rebecca Kavoussi
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