Results 41 to 50 of about 5,138,464 (395)

Youth Marijuana and Prescription Drug Abuse in Anchorage [PDF]

, 2016
Complete issue of Alaska Justice Forum 33(1), Spring 2016 at https://scholarworks.alaska.edu/handle/11122/6883.This article examines results of the Adult Perceptions of Anchorage Youth: 2015 Survey (APAYS) to examine perceptions and concerns of Anchorage
Lepage, Cory R., Rivera, Marny
core  

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song, Jonathan Baron, Carlos Chavez Perez, Sidharth Ramesh, Jane Minturn, Kavita A. Desai, Amish C. Shah, Jean M. Belasco, Kristina A. Cole, Michael J. Fisher, Phillip B. Storm, Peter M. Madsen, Goldie Kurtz, Robert A. Lustig, Christine Hill‐Kayser, Michael J. LaRiviere   +15 more
wiley   +1 more source

Public and health care provider attitudes, understanding, and behaviors regarding emergency use authorizations: a scoping literature review

BMC Public Health
Background Under Sect. 564 of the Federal Food, Drug, and Cosmetic Act, when the US Department of Health and Human Services Secretary issues a declaration based on one of four types of determinations, FDA may authorize an unapproved product or unapproved
Caroline Rains, Kathryn J. Aikin, Helen W. Sullivan, Bridget J. Kelly, Shirley Liu, Camara Wooten, Jenna Brophy, Susana Peinado, Lauren McCormack, Sandra Crouse Quinn   +9 more
doaj   +1 more source

Interactive exploration of population scale pharmacoepidemiology datasets

, 2020
Population-scale drug prescription data linked with adverse drug reaction (ADR) data supports the fitting of models large enough to detect drug use and ADR patterns that are not detectable using traditional methods on smaller datasets. However, detecting
Abadi M., Furu K., Salathé M., Ventola C. L., Wishart D. S.   +4 more
core   +1 more source

A survey of substance use for cognitive enhancement by university students in the Netherlands [PDF]

, 2015
Background: Pharmacological cognitive enhancement, using chemicals to change cellular processes in the brain in order to enhance one's cognitive capacities, is an often discussed phenomenon.
Bundt, Carsten, Gusman-Vermeer, Joyce, Olthof, Bas, Reintjes, Wesley, Schelle, Kimberly, van Mil, Anke   +5 more
core   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Preventing prescription drug abuse

Cleveland Clinic Journal of Medicine, 2000
Prescription drug abuse is a problem with potentially grave consequences for patients and their families. Primary care physicians can play a major role in curbing prescription drug abuse by learning to recognize drug-seeking behavior and other warning signs, by educating patients about their drug regimens, and by setting firm but reasonable prescribing
W. S. WILKE, J. H. ISAACSON
openaire   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Syrup Amkesol reduces the level of primary and secondary products of lipid peroxidation and toxic metabolites of nitric oxide in blood serum of immature rats with bronchiolitis

Annals of Mechnikov's Institute, 2019
Aim of this study was to determine the pharmacological effect of syrup Amkesol evaluating the blood serum levels of primary and secondary products of lipid peroxidation, activity of AO enzymes and final rates of NO metabolites in immature rats of ...
K Storozhenko
doaj