Results 31 to 40 of about 503,750 (348)

Predictors of Antibiotics Co-prescription with Antimalarials for Patients Presenting with Fever in Rural Tanzania. [PDF]

, 2013
Successful implementation of malaria treatment policy depends on the prescription practices for patients with malaria. This paper describes prescription patterns and assesses factors associated with co-prescription of antibiotics and artemether ...
A Mannan, Alexander N Dodoo, ANO Dodoo, B Ahsan, BK Abuaku, BP Mmbando, Brown Kigahe, C Watsierah, CIR Chandler, CIR Chandler, D Zurovac, Dan Kajungu, EME Van Bijnen, F Font, F Font, H Reyburn, H Reyburn, H Riaz, I Masanja, I Tamuno, Ifakara, IM Masanja, Irene Masanja, JR Torvi, JU Okebe, K Bashrahil, K Shamshy, KA Oshikoya, LEG Mboera, Majige Selemani, Mbaraka Amuri, MI Masanja, ML McMorrow, ML Mcmorrow, Mustafa Njozi, Mwageni, N Nshakira, National Malaria Control Programe (NMCP) [Tanania], National Malaria Control Programme (NMCP) [Tanzania], P Winskill, Rashid Khatib, Salim Abdula, TO Ogungbamigbe, VA Badar   +43 more
core   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

An inevitable wave of prescription drug monitoring programs in the context of prescription opioids: pros, cons and tensions [PDF]

, 2014
BACKGROUND: In an effort to control non-medical use and/or medical abuse of prescription drugs, particularly prescription opioids, electronic prescription drug monitoring programs (PDMP) have been introduced in North-American countries, Australia and ...
Islam, M. Mofizul, McRae, Ian S.
core   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Prescription drug dependence with and without concurrent illicit drug use: a multicenter cross-sectional survey among an addiction treatment seeking population

Frontiers in Psychiatry, 2023
BackgroundDependence on prescription drugs and illicit drugs imposes a global health and social burden. Despite accumulating evidence of prescription drugs and illicit drugs dependence, none of the systematized studies has explored the magnitude of this ...
Asma Nawaz, Suzanne Nielsen, Tahir Mehmood, Abdullah Abdullah, Ali Ahmed, Waseem Ullah, Ahmad Khan   +6 more
doaj   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Off-label prescription of drugs at hospital [PDF]

Farmacia Hospitalaria, 2016
Objectives: To develop a procedure for management of off-label medications, and to analyze the treatments, indications, and hospital units which will request them more frequently, as well as which variables will have an impact on the authorization ...
Vicente Arocas Casañ, Jaime Mateo Carmona, Olga García Molina, Mº Ángeles Fernández de Palencia Espinosa, Mª José Blázquez Álvarez Espinosa, Mª Amelia de la Rubia Nieto, Jesús del Río García   +6 more
doaj   +1 more source

Prescription Audit for WHO Prescribing Indicators and Prescription Errors in a Tertiary Care Teaching Hospital

Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2023
Aim: Our study aimed to audit prescriptions for the prescription indicators given by WHO and to analyze prescription errors, evaluating the frequency and types of prescription errors. Methodology: Prospective study was done in Dr. D. Y.
Sarita Mulkalwar, Abhi Patel, Sudeep David, Krushal Pabari, Praveen Math, Abhijeet V. Tilak   +5 more
doaj   +1 more source

Preventing prescription drug abuse

Cleveland Clinic Journal of Medicine, 2000
Prescription drug abuse is a problem with potentially grave consequences for patients and their families. Primary care physicians can play a major role in curbing prescription drug abuse by learning to recognize drug-seeking behavior and other warning signs, by educating patients about their drug regimens, and by setting firm but reasonable prescribing
W. S. WILKE, J. H. ISAACSON
openaire   +2 more sources

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source