Results 91 to 100 of about 42,897 (306)
Update on prescription extended-release opioids and appropriate patient selection
Michael J Brennan The Pain Center of Fairfield, Fairfield, CT, USA Abstract: Chronic pain is largely underdiagnosed, often undertreated, and expected to increase as the American population ages. Many patients with chronic pain require long-term treatment
Brennan MJ
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Quantification of classic, prescription and synthetic opioids in hair by LC–MS-MS
The current use and misuse of synthetic and prescription opioids in the USA has reached epidemic status. According to the US Department of Health and Human Services, every day more than 130 people in the USA die after overdosing on opioids, and 2.1 ...
Lendoiro, Elena +5 more
core +1 more source
Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga +20 more
wiley +1 more source
Trends in Prescription Opioids Detected in Fatally Injured Drivers in 6 US States: 1995–2015
Objectives. To assess the time trends in prescription opioids detected in fatally injured drivers. Methods. We analyzed 1995 to 2015 Fatality Analysis Reporting System data from California, Hawaii, Illinois, New Hampshire, Rhode Island, and West ...
Stanford Chihuri, Guohua Li
core +1 more source
Background Reporting adverse drug reactions (ADRs) is essential for drug safety. In Switzerland, healthcare professionals are legally required to report serious and unlabelled ADRs, yet under‐reporting remains widespread. We tested a novel method to increase reporting of ADR‐related hospitalizations.
Georgia Anita Weber +7 more
wiley +1 more source
Prescription of opioids for breathlessness in end-stage COPD: a national population-based study
Zainab Ahmadi,1,2 Eva Bernelid,2 David C Currow,3 Magnus Ekström1–3 1Department of Clinical Sciences, Division of Respiratory Medicine and Allergology, Lund University Hospital, Lund, 2Department of Medicine, Blekinge Hospital, Karlskrona ...
Ahmadi Z +3 more
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Precision medicine in paediatrics: Progress and priorities
Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain +3 more
wiley +1 more source
The use of prescription opioids for chronic non-cancer pain is complex. Opioids have the potential to alleviate discomfort and increase ones overall ability to function but, long term use also has potential physical and psychological impacts.
Brooks, Erica
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Exploring new avenues: Psychedelic‐assisted therapy for young people
Rates of mental illness in young people are increasing, whereas the development of novel mental health treatments has not significantly progressed. Psychedelic‐assisted therapy, using substances such as psilocybin and 3,4‐methylenedioxymethamphetamine (MDMA), has shown potential in the treatment of mental illnesses in the adult population, including ...
Ioanna Artemis Vamvakopoulou +3 more
wiley +1 more source
Pain management, prescription opioid mortality, and the CDC: is the devil in the data?
Michael E Schatman,1,2 Stephen J Ziegler31Research and Network Development, Boston Pain Care, Waltham, MA, 2Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, 3Department of Public Policy, Purdue University, Fort Wayne,
Schatman ME, Ziegler SJ
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