Results 221 to 230 of about 16,598,179 (322)

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

RivFISH - An European database on fish species presence across river basins

open access: green
Daniel Mameri   +7 more
openalex   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Neutrophils and aortic medial amyloid: mutually beneficial or a dangerous combination? [PDF]

open access: yesFront Immunol
Maerivoet A   +5 more
europepmc   +1 more source

Impact of listener presence on gesture production during scripted storytelling and explanation of unknown words.

open access: green
Gerlind Große   +5 more
openalex   +1 more source

In the Presence of Death

open access: yes, 2014
Lavery, Kevin P.
core  

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