Results 261 to 270 of about 16,598,179 (322)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Higher consumption of ultra-processed foods is associated with disordered eating symptoms and low-quality diet in adults with obesity. [PDF]

Arch Endocrinol Metab
Favaron CM, Mônico-Neto M, Antunes HKM, Bittencourt LRA, Galvão TD, Tufik S, Campos RMDS.   +6 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Enhanced Efficacy of Laser-Activated Irrigation (Er,Cr:YSGG) in Eradicating Enterococcus faecalis Biofilm in 3D-Printed Molar Replicas: A Pilot Study. [PDF]

Clin Exp Dent Res
Macedo M, Albernaz Neves J, Pérez AR, Proença L, Bessa LJ.   +4 more
europepmc   +1 more source

STRUCTURE DE LA TURBULENCE PARIETALE EN PRESENCE DE DIFFERENCE DE DENSITE

, 2002
A. Soudani
openalex   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Editorial: Working mechanisms of design elements to facilitate learning in extended reality

Frontiers in Virtual Reality
Katharina Jahn, Günter Daniel Rey, Dezhi Wu, Bastian Kordyaka   +3 more
doaj   +1 more source

Tertiary lymphoid structures in genitourinary cancers: a comprehensive review. [PDF]

Front Oncol
Abreu A, Viera Plasencia A, Iribarren M, Wegner C, Nuraj J, Davicioni E, Bahmad HF, Shahait M.   +7 more
europepmc   +1 more source

Presence of Salmonella, Escherichia coli O157 and Campylobacter in small-ruminants

, 2015
K. E. Hanlon
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source