Results 191 to 200 of about 449,359 (249)

Pregnant Women's Experiences of Obstetric Abdominal Ultrasound: A Qualitative Study Exploring Emotional, Cognitive, and Relational Dimensions. [PDF]

Healthcare (Basel)
Sezer Balci A, Bayrak CC, Akpınar Alaoglu M.   +2 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Meaning-making coping under the threat of war: a qualitative study of people in Sweden. [PDF]

Front Sociol
Darvishpour Z, Ahmadi F, Cetrez ÖA.
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

The differential associations of reminiscence and exploratory travel with late-life psychological well-being: A prospective cohort study. [PDF]

Medicine (Baltimore)
Li R, Zhao N.
europepmc   +1 more source

Predictors of psychological resilience among high-risk professionals: a two-year follow-up study in Dutch firefighters. [PDF]

Eur J Psychotraumatol
Lenaert B, Barry TJ, Ten Hertog I, Lommen MJJ.   +3 more
europepmc   +1 more source

Positive childhood experiences and life satisfaction among Chinese college students: serial mediation through perceived social support and meaning in life. [PDF]

Front Psychiatry
Yang Y, Chen P, Chen Z, Lei P.
europepmc   +1 more source