Results 101 to 110 of about 321,867 (325)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Presence

open access: yes, 2002
Presence-projektissa tutkittiin läsnäolon tunnetta tietotekniikan avulla luoduissa ympäristöissä. Virtuaalisen läsnäolon tunne on monitahoinen käsite, jota tarkasteltiin eri kannoilta. Tutkimuksessa selvitettiin läsnäolon tunteen eri tyyppejä, siihen vaikuttavia tekijöitä sekä sen seurauksia, hyötyjä ja haittoja.
Välkkynen Pasi, Mokka Sari
openaire   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Transgressive Knowing

open access: yesJournal of Awareness-Based Systems Change
This issue's In-Dialogue represents the intentional epitomization of many conversations the Editorial Team has been having since JASC’s inception around what we mean by 'transformative'.
Oliver Koenig   +7 more
doaj   +1 more source

The captive [PDF]

open access: yes
Text of a response to a paper by Linda Lai - ‘Presencing the past, a montage experience: walking through a series of temporal nodes’ - at Urban Encounters 2017: Cartographies, Clore Auditorium, Tate Britain, November 11 ...
Dowd, Garin
core  

Development of Nurse Presence Scale [PDF]

open access: bronze, 2001
Kae Hwa Jo, Young Suk Cho
openalex   +1 more source

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