Results 111 to 120 of about 321,867 (325)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The visible and invisible in making: reflecting on a personal practice [PDF]
, 2012 In this paper I reflect upon the nature of making within my own practice, with specific reference to intrapersonal conversations (Bolt) and those with materials.
Piper, GF
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Siting Foreign Law: How Derrida Can Help [PDF]
, 2011 Secondary spectrum access to TV white spaces is considered as a promising solution to relieve the spectrum shortage. In Europe, SE43 working group in CEPT is leading the discussion on the technical requirements for exploiting TV white spaces through the ...
Legrand, Pierre
core +2 more sources
Perilous presencing: How the church’s sacraments re-symbolize trauma
Acta TheologicaThis article examines the church’s sacramental life – baptism and the Eucharist – as enactments of trauma that mirror Christ’s suffering and death, shaping its vocation of self-giving for a broken world.
A. Lau
doaj +1 more source
"Saturday Night Seder" and the Affordances of Cultural Arts during COVID-19. [PDF]
Contemp Jew, 2021 Yares L, Avni S.
europepmc +1 more source
The inclusions afforded by a value-led design process for technology-nature hybrids in a walled kitchen garden [PDF]
, 2015 This paper describes the importance of a values-led approach within a design collaboration in a National Trust garden in Nottinghamshire, UK. The project demonstrates the power of values to shape not only the designed artefacts but the whole design ...
Chiasson, Mike +2 more
core
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
, 2011 Most celebrated artists are as influential artistically as they are critically. Beuys’ reception to date, remains controversial and contradictory; his artistic influence is unquestioned but this is not matched by his critical acclaim.
Foster, Nicola
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source