Results 101 to 110 of about 46,260,578 (335)

The Democratic Impact of ICT in Africa Informations- und Kommunikationstechnologien, politische Handlungsfähigkeit und demokratisches Regieren in Afrika

open access: yesAfrica Spectrum, 2012
This paper takes a critical look at the view that the Internet can serve as a laboratory of political experimentation for reconfiguring the repertories of political actions.
Alexandra Dobra
doaj  

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

open access: yesFEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson   +7 more
wiley   +1 more source

Câteva aspecte dominante ale gândirii filosofice la omul contemporan [PDF]

open access: yesEon
The work systematizes several essential aspects of contemporary man. It reveals his trinitarian structure: body, soul, and spirit. His temporal trivalence - past, present, and future. The process of psycho-intellectual maturation. His essential dimension
Teodor VIDAM
doaj   +1 more source

Globalisation's Effects on World Agricultural Trade, 1960 to 2050 [PDF]

open access: yes
Recent globalisation has been characterised by a decline in costs of cross-border trade in farm and other products. It has been driven primarily by the information and communication technology revolution and – in the case of farm products – by ...
Kym Anderson
core  

Present distribution of the threatened killifish Aphanius fasciatus (Actinopterygii, Cyprinodontidae) in the Maltese Islands [PDF]

open access: yes, 2002
A survey of the nine localities from which the threatened Killifish Aphanius fasciatus has been recorded in the Maltese Islands showed that large and thriving populations exist at Salina, at the Simar and Ghadira bird sanctuaries and in reservoirs at ...
Arcidiacono, Isabella   +3 more
core  

Dune formation on the present Mars

open access: yes, 2007
We apply a model for sand dunes to calculate formation of dunes on Mars under the present Martian atmospheric conditions. We find that different dune shapes as those imaged by Mars Global Surveyor could have been formed by the action of sand-moving winds
Eric J. R. Parteli   +17 more
core   +1 more source

Mechanisms and kinetic assays of aminoacyl‐tRNA synthetases

open access: yes
FEBS Letters, EarlyView.
Igor Zivkovic   +2 more
wiley   +1 more source

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