Results 181 to 190 of about 19,830,962 (273)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Brow Presentation [PDF]

BMJ, 1961
openaire   +2 more sources

Atrophic Dermatofibroma: A Rare Variant With Distinct Clinical and Histopathological Features. [PDF]

Case Rep Dermatol Med
Althobaiti RF, Alharbi JK, Alabbadi A, Zafer D, Alluhaibi R, Hafiz BZ.   +5 more
europepmc   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Oral Presentations and Poster Presentations

British Journal of General Practice, 2020
openaire   +3 more sources

Antidiscrimination Laws and Kidney Transplant for Patients With Developmental Disabilities.

JAMA Intern Med
Hand BN, Hyer JM, Nikahd M, Gothard A, Brock G, Gardner J, Bishop L, Shea L, Wang L, Schenk AD.   +9 more
europepmc   +1 more source

Net present value analysis of total salary compensation in hand surgery: academic versus non-academic careers. [PDF]

Arch Orthop Trauma Surg
Moore JW, Minerva AJ, Daley DN, Daly CA, Silvestre J.   +4 more
europepmc   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Can ICD-11 Personality Disorder Trait Dimensions Be Categorically Specified? [PDF]

Personal Ment Health
Grunert GV, Simonsen E, Kongerslev MT, Bach B.   +3 more
europepmc   +1 more source