Results 221 to 230 of about 47,925,041 (381)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Beyond the perception of present economic inequality: How people construe past, present and future wealth gaps. [PDF]

PLoS One
Scatolon A, Galdi S, Cervone C, Mannetti L, Maass A.   +4 more
europepmc   +1 more source

7-Methylguanine adducts in DNA are normally present at high levels and increase on aging: analysis by HPLC with electrochemical detection.

, 1988
J W Park, B N Ames
openalex   +2 more sources

Groundwater governance in Asia: present state and barriers to implementation of good governance [PDF]

, 2014
Tadashi Tanaka
openalex   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Birds of Faynan: past and present [PDF]

, 2019
Greet, Benjamin, Khoury, Fares, Maslamani, Nebras, Mithen, Steve, White, Judy   +4 more
core   +1 more source

Correction: Chronic administration of Metformin exerts cytostatic and cytotoxic effects via the PP2A-GSK3β-MCL-1 pathway by inhibiting the tmCLIC1 membrane protein in glioblastoma-initiating cells. [PDF]

J Exp Clin Cancer Res
Cianci F, Verduci I, Cazzoli R, Cannavale G, Rey G, Veronesi M, Balboni B, Ranucci M, Palloni LMG, Ballabio F, Barsotti N, Ailuno G, Balboni A, Baldassari S, Caviglioli G, Tacconi C, Camilloni C, Girotto S, Fantin A, Barbieri F, Cavalli A, Pasqualetti M, Florio T, Minucci S, Mazzanti M.   +24 more
europepmc   +1 more source

Psychiatric Disorders in Patients Presenting to the Emergency Department for Minor Injury

, 2007
Therese S. Richmond, Judd E. Hollander, Theimann H. Ackerson, Keith Robinson, Vicente H. Gracias, Justine Shults, Jay D. Amsterdam   +6 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Projections of 21st-century sea-level fall along coastal Greenland. [PDF]

Nat Commun
Lewright L, Austermann J, Piecuch CG, Adhikari S, Davis JL, Milne GA, Paxman GJG.   +6 more
europepmc   +1 more source