Results 41 to 50 of about 16,233,204 (291)

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Robert Merle théoricien et praticien de la politique-fiction

open access: yesReS Futurae, 2016
In the 70’s, in the midst of the Cold War, a literary genre, both disregarded and often described as "hybrid”, – political fiction – develops in Anglo-Saxon countries.
Anne Wattel
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

Présent rétrospectif et détour post-humain chez Clifford Simak et Michel Houellebecq

open access: yesReS Futurae, 2016
This article draws a comparison between City by Clifford Simak and The Possibility of an Island by Michel Houellebecq. Both novels demonstrate the same kind of narratological device: our time (1950-2005) is portrayed by a narrating voice from beyond ...
Juliette Feyel
doaj   +1 more source

Screen Present and Fictional Present [PDF]

open access: yesManuscrito, 2016
ABSTRACT I intend in this paper to explore the possible consequences for our understanding of fiction of a particular view of the nature of time, namely the hypothesis of the open future. The kind of fiction we will particularly concerned with is film, which provides a convenient way of focusing the general issue I want to raise here.
openaire   +4 more sources

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

Presentism without Presentness [PDF]

open access: yesThought: A Journal of Philosophy, 2015
We argue that presentism, understood as a view about time and existence, can perspicuously be defined in opposition to all other familiar contenderswithout appeal to any notion of presentness or cognate notions such as concreteness. Given recent worries about the suitability of such notions to cut much metaphysical ice, this should be welcomed by ...
Correia Fabrice, Rosenkranz Sven
openaire   +2 more sources

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

La complejidad en la totalidad dialéctica Complexity in dialectical totality

open access: yesSociologias, 2006
El trabajo parte de mostrar las limitaciones de los discursos sustantivos disciplinarios. Enseguida se expone la complejidad los conceptos de realidad, presente y utopía, para con ello, discutir cómo ocurre la producción de conocimiento científico, pero ...
Carlos Massé Narváez
doaj   +1 more source

Home - About - Disclaimer - Privacy