Results 131 to 140 of about 933 (250)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Analiza niezawodności konstrukcji wsporczej poddanej działaniu drgań wymuszonych

, 2015
The study concerns the forced vibrations analysis of supporting structure in terms of probabilism. Structural design parameters are defined as the deterministic values and random variables. Random variables are not correlated.
Dudzik, A., Radoń, U.
core  

Finite element analysis of flexural behavior in ultra-high-strength concrete beams with BFRP and hybrid BFRP-steel reinforcement. [PDF]

Sci Rep
Ali NM.
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

A Digital Twin Framework for Structural Health Monitoring of Existing Large-Span Bridges. [PDF]

Sensors (Basel)
Tran MQ, Sousa HS, Matos JC, Dang SN, Nguyen HX.   +4 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Assessment on Pavement Performance and Remaining Life cycle Analysis Using Integrated HDM-4 Software: Case Study within Kombolcha-Harbu Road section

, 2017
Transportation facilities constitute one of the most valuable public assets that account for a major share of public sector investment in the world.
Esayas Alemayehu, Mohammed Yimam, Tarekegn Kumela   +2 more
core  

Preliminary Assessment of Commercial Antibacterial Finishes on Knitted Fabrics from Recycled Cotton and Polyester. [PDF]

Materials (Basel)
Faheem MS, Jamshaid H, Mishra RK, Abbas A, Muller M, Urban J, Penc M.   +6 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Serviceability and ductility behaviour of hybrid reinforced concrete beams partially composed of engineered cementitious composite (ECC). [PDF]

Sci Rep
Radwan AA, Ghallab A, Maree AMF.
europepmc   +1 more source