Results 71 to 80 of about 933 (250)

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi   +6 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

A Study on the Establishment of Domestic Freeways Pavement Serviceability Models

open access: yes, 2010
鋪面服務能力或行駛品質之評量是鋪面管理系統中非常重要之項目,本文主要內容為回顧國內外高速公路鋪面功能性評估之文獻,選擇中山高速公路與北部第二高速公路柔性鋪面路段進行鋪面現況服務能力評分(PSR)試驗與鋪面糙度調查,所得數據整理分析後,建立現況服務能力指標(PSI)預測模式,以供國內鋪面養護管理單位參考。This paper is to describe a preliminary study on the establishment of domestic pavement serviceability
劉明仁; 江煌基   +1 more
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Multidisciplinary design and optimization of gas turbine engine low pressure turbine at preliminary design stage

open access: yes, 2014
The gas turbine engine has evolved rapidly during past decades to provide a reliable and efficient business solution for global transportation. The engine design process is clearly a large contributor to this evolution.
Bar, W., Moustapha, H., Orkisz, M.
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The Project Management Maturity Model and Application Based on PRINCE2

open access: yes, 2012
Project management maturity model is regarded as a useful tool to evaluate organizations’ current project management capability. Through literature review, we build up a new kind of project management maturity model called P2CMM based on the attribute ...
Jing, He   +2 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The IJK Ride Indicator, 1976

open access: yes, 1976
State highway engineers realized a need for a numerical quality index and began planning for a research project of this type in 1951. The Present Serviceability Index was developed through the AASHO (now AASHTO) Road Test near Ottawa, Illinois, from 1956

core  

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