Results 121 to 130 of about 310,989 (265)

Evaluation of a Room-Temperature Preservation Method Maintaining Viability and Function in Human Cardiac Organoids. [PDF]

Cells
Van Rompay C, Tabury K, Rehnberg E, Janssen Z, Baatout S, Carlon MS, Solvas XCI, Baselet B.   +7 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Evaluating effects of tissue type, preservation method, and decomposition on DNA quality to support genetic sampling in stranded small cetaceans. [PDF]

Sci Rep
Grilo ML, Leal E Rigor M, Moura AE, Avellaneda K, Gross S, Robalo JI, Ceia FR, Siebert U.   +7 more
europepmc   +1 more source

Effects of preservation method on canine (Canis lupus familiaris) fecal microbiota. [PDF]

PeerJ, 2018
Horng KR, Ganz HH, Eisen JA, Marks SL.
europepmc   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

An improved preservation method for human dorsal root ganglion neurons enables wider access to human molecular pain neuroscience. [PDF]

Cell Rep Methods
Lesnak JB, Schaub MK, Gomez K, Calderon-Rivera A, Loya-Lopez S, Stewart R, Jo S, Fujita A, Osorno T, Mydugolam H, Desai M, Natarajan K, Schackmuth MK, Moreno MM, Shiers SI, Cervantes A, Funk G, Horton P, Vines E, Yousuf MS, Sadler KE, Bean BP, Khanna R, Dussor G, Price TJ.   +24 more
europepmc   +1 more source

Impact of Preservation Method and 16S rRNA Hypervariable Region on Gut Microbiota Profiling. [PDF]

mSystems, 2019
Chen Z, Hui PC, Hui M, Yeoh YK, Wong PY, Chan MCW, Wong MCS, Ng SC, Chan FKL, Chan PKS.   +9 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Optimal Preservation Method for Long-term Preservation in ddH₂O and Starvation Adaptive Mechanisms of Flavobacterium columnare Revealed by Multi-omic Analysis. [PDF]

Microb Ecol
Gao S, Zhong L, Zhang Y, Zhu R, Shao Y, Li R, Zhu Y, Cai W.   +7 more
europepmc   +1 more source