Background This study investigated Lp(a) (lipoprotein(a)) levels with heart failure (HF) incidence overall and ejection fraction (EF) subtypes among Black and White participants in a pooled analysis of MESA (Multi‐Ethnic Study of Atherosclerosis), FOS ...
Sarah Nomura +10 more
doaj +1 more source
Western Diet-Fed, Aortic-Banded Ossabaw Swine: A Preclinical Model of Cardio-Metabolic Heart Failure. [PDF]
The development of new treatments for heart failure lack animal models that encompass the increasingly heterogeneous disease profile of this patient population.
Alex, Linda +22 more
core
‘Hearts and minds’: association, causation and implication of cognitive impairment in heart failure [PDF]
The clinical syndrome of heart failure is one of the leading causes of hospitalisation and mortality in older adults. An association between cognitive impairment and heart failure is well described but our understanding of the relationship between the ...
Cannon, Jane A. +2 more
core +4 more sources
Radiation‐Resistant Aluminum Alloy for Space Missions in the Extreme Environment of the Solar System
A novel ultrafine‐grained aluminum crossover alloy exhibits unprecedented radiation resistance and mechanical stability under extreme irradiation doses up to 100 dpa. The exceptional resilience arises from thermodynamically stable T‐phase precipitates, enabling lightweight structural materials for next‐generation spacecraft and extraterrestrial ...
Patrick D. Willenshofer +9 more
wiley +1 more source
Inter-atrial block and atrial fibrillation predict cardiac adverse events in heart failure with preserved ejection fraction [PDF]
Jerremy Weerts +9 more
openalex +1 more source
Right ventricular outflow tract velocity time integral-to-pulmonary artery systolic pressure ratio: a non-invasive metric of pulmonary arterial compliance differs across the spectrum of pulmonary hypertension. [PDF]
Pulmonary arterial compliance (PAC), invasively assessed by the ratio of stroke volume to pulmonary arterial (PA) pulse pressure, is a sensitive marker of right ventricular (RV)-PA coupling that differs across the spectrum of pulmonary hypertension (PH ...
Bhattacharya, Priyanka T. +15 more
core +2 more sources
A novel immunotherapeutic strategy combines injectable, adjuvant‐loaded hydrogels with externally controlled histotripsy to create immune‐priming sites within tumors. This approach generates millimeter‐sized immune‐activated lesions with flexible, patient‐tailored treatment scheduling, enabling precise immune activation through tumor ablation‐mediated ...
Sung Hoon Kim +9 more
wiley +1 more source
Towards Metabolomic-Based Precision Approaches for Classifying and Treating Heart Failure
Summary: Both heart failure and cardiometabolic disease are on the rise, and abnormal cardiac and peripheral metabolism are central to the syndrome of heart failure.
Virginia S. Hahn, MD +3 more
doaj +1 more source
Objective: to analyze the level of neopterin in patients with chronic heart failure (CHF) with a preserved fraction ejection fraction depending on the stage of the disease.
O. S. Polunina +3 more
doaj +1 more source
Response to pulmonary arterial hypertension drug therapies in patients with pulmonary arterial hypertension and cardiovascular risk factors. [PDF]
The age at diagnosis of pulmonary arterial hypertension (PAH) and the prevalence of cardiovascular (CV) risk factors are increasing. We sought to determine whether the response to drug therapy was influenced by CV risk factors in PAH patients. We studied
Charalampopoulos, A +9 more
core +1 more source

