Results 141 to 150 of about 410,320 (404)

Molecular biomarker profile of heart failure with mid-range and preserved ejection fraction in patients with type 2 diabetes

Российский кардиологический журнал, 2020
Aim. To study molecular biomarkers in patients with type 2 diabetes (T2D) in combination with heart failure with preserved (HFpEF) and mid-range ejection fraction (HFmrEF) and compare the data obtained with clinical characteristics of myocardial ...
D. A. Lebedev, E. A. Lyasnikova, A. A. Vasilyeva, E. Yu. Vasilyeva, A. Yu. Babenko, E. V. Shlyakhto   +5 more
doaj   +1 more source

Heart Failure With Preserved Ejection Fraction In Perspective.

Circulation Research, 2019
Approximately half of the patients with signs and symptoms of heart failure have a left ventricular ejection fraction that is not markedly abnormal. Despite the historically initial surprise, heightened risks for heart failure specific major adverse ...
M. Pfeffer, A. Shah, B. Borlaug
semanticscholar   +1 more source

Empagliflozin improves endothelial and cardiomyocyte function in human heart failure with preserved ejection fraction via reduced pro-inflammatory-oxidative pathways and protein kinase Gα oxidation.

Cardiovascular Research, 2020
AIMS Sodium-glucose-cotransporter-2 (SGLT2) inhibitors showed favourable cardiovascular outcomes, but the underlying mechanisms are still elusive. This study investigated the mechanisms of empagliflozin in human and murine heart failure with preserved ...
D. Kolijn, S. Pabel, Yanna Tian, M. Lódi, M. Herwig, A. Carrizzo, S. Zhazykbayeva, Á. Kov́acs, G. Fülöp, I. Falcão-Pires, Peter H. Reusch, S. Linthout, Z. Papp, L. van Heerebeek, C. Vecchione, L. Maier, M. Ciccarelli, C. Tschöpe, A. Mügge, Z. Bagi, S. Sossalla, N. Hamdani   +21 more
semanticscholar   +1 more source

Isosorbide Mononitrate in Heart Failure with Preserved Ejection Fraction. [PDF]

, 2015
BACKGROUND: Nitrates are commonly prescribed to enhance activity tolerance in patients with heart failure and a preserved ejection fraction. We compared the effect of isosorbide mononitrate or placebo on daily activity in such patients.
Anstrom, Kevin J., Borlaug, Barry A., Braunwald, Eugene, Chen, Horng H., Cole, Robert T., Felker, G. Michael, Joseph, Susan M., Koepp, Gabe A., Levine, James A., LeWinter, Martin M., McNulty, Steven E., Redfield, Margaret M., Reeves, Gordon R., Semigran, Marc J., Shah, Monica R, Shah, Sanjiv J., Tang, W.H. Wilson, Tedford, Ryan J., Velazquez, Eric J.   +18 more
core   +2 more sources

Research on the Evolution of Defects Initiation and the Diffusion of Dopant on the Si/SiO2 Interface

Advanced Materials Interfaces, EarlyView.
This review mainly introduces the recent investigations on the mechanisms of interface defect initiation and dopant diffusion, and the comparisons and discussions of the initial mechanism of defects, structures of defects to provide valuable guidance for improving the performance and extending the lifespan of Si/SiO2 interfaces.
Yunqi Yang, Dongdong Chen, Di Li, Tianlong Zhao, Weida Zhang, Wen Qiao, Yingjie Liang, Yintang Yang   +7 more
wiley   +1 more source

Clinical and prognostic value of determining the level of neopterin in patients with chronic heart failure with preserved ejection fraction

Медицинский вестник Юга России, 2018
Objective: to analyze the level of neopterin in patients with chronic heart failure (CHF) with a preserved fraction ejection fraction depending on the stage of the disease.
O. S. Polunina, L. P. Voronina, I. V. Sevostyanova, E. A. Polunina   +3 more
doaj   +1 more source

Effect of Vericiguat vs Placebo on Quality of Life in Patients With Heart Failure and Preserved Ejection Fraction: The VITALITY-HFpEF Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2020
Importance Patients with heart failure and preserved ejection fraction (HFpEF) are at high risk of mortality, hospitalizations, and reduced functional capacity and quality of life.
P. Armstrong, C. Lam, K. Anstrom, J. Ezekowitz, Adrian F. Hernandez, C. O'connor, B. Pieske, P. Ponikowski, Sanjiv J. Shah, S. Solomon, A. Voors, Lilin She, Vanja Vlajnic, F. Carvalho, L. Bamber, R. Blaustein, L. Roessig, J. Butler   +17 more
semanticscholar   +1 more source

Impact of left ventricular ejection fraction on clinical outcomes after left main coronary artery revascularization [PDF]

, 2020
Aim: To evaluate the impact of left ventricular ejection fraction (LVEF) on 3-year outcomes in patients with left main coronary artery disease (LMCAD) undergoing percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) in the ...
Crowley, A. (Aaron), Dressler, O. (Ovidiu), Head, S.J. (Stuart), Kappetein, A.P. (Arie Pieter), Milojevic, M. (Milan), Puskas, J.D. (John), Sabik, J.F. (Joseph), Serruys, P.W.J.C. (Patrick), Stone, G.W. (Gregg), Thuijs, D.J.F.M. (Daan)   +9 more
core   +1 more source

Investigation of Solid‐State Interface Reactions Between the Compositionally Complex Solid Solution Noble Metal Alloy Ag‐Au‐Pd‐Pt and Si

Advanced Materials Interfaces, EarlyView.
Combinatorial sputtering of a compositionally complex Ag‐Au‐Pd‐Pt solid solution on pre‐sharpened Si microtip arrays enabled the investigation of interface reactions between the film and Si using a semi‐correlative atom probe tomography/transmission electron microscopy analysis for near atomic‐scale characterization without additional sample ...
Yujiao Li, Aleksander Kostka, Alan Savan, Alfred Ludwig   +3 more
wiley   +1 more source

Cognitive function in late‐stage HFpEF patients with tricuspid regurgitation undergoing transcatheter tricuspid valve intervention

Catheterization and Cardiovascular Interventions, Volume 100, Issue 7, Page 1323-1330, December 1, 2022., 2022
Abstract Objectives This study evaluates the impact of transcatheter tricuspid valve interventions (TTVI) on cognitive function (CF), quality of life (QOL), and exercise capacity in late‐stage heart failure with preserved ejection fraction (HFpEF) and relevant tricuspid regurgitation (TR).
Muhammed Gerçek, Anca A. Irimie, Mustafa Gerçek, Henrik Fox, Vera Fortmeier, Tanja K. Rudolph, Volker Rudolph, Kai P. Friedrichs   +7 more
wiley   +1 more source