Results 251 to 260 of about 124,550 (291)

Heart failure with preserved ejection fraction and obesity: emerging metabolic therapeutic strategies. [PDF]

Diabetol Metab Syndr
Zheng W, Qi Q, Li J, He C, Fan H.
europepmc   +1 more source

Development of an efficient mice model of cancer‐associated cardiac cachexia

Animal Models and Experimental Medicine, EarlyView.
This work establishes a preclinical framework for targeting ubiquitin pathways to mitigate the morbidity of cancer‐related cardiopathy. Our integrated approach delineates a hierarchical progression from subcellular dysfunction to macroscopic cardiac deterioration. These findings mechanistically link tumor‐induced cachexia to cardiac dysfunction through
Shijie Xiong, Huiting Zheng, Teng Wu, Jing Tan, Tongsheng Huang, Conghui Shen, Yuanjun Ji, Mengying Liu, Junhong Wan, Weibin Cai   +9 more
wiley   +1 more source

Serum Oxysterol Levels in Heart Failure With Preserved Ejection Fraction: A Prospective Case-Control Study. [PDF]

Cureus
Dagli M, Kerkütlüoğlu M, Alkan Baylan F, Gunes H.   +3 more
europepmc   +1 more source

A Novel Transcriptional Slippage Mechanism Rescues Dystrophin Expression from a DMD Frameshift Variant

Annals of Neurology, EarlyView.
Pathogenic DMD variants usually follow the reading‐frame rule: out‐of‐frame changes cause Duchenne muscular dystrophy, whereas in‐frame ones produce Becker muscular dystrophy (BMD). We report a 23‐year‐old man with BMD‐like weakness, calf hypertrophy, elevated creatine kinase, and dilated cardiomyopathy.
Hiroya Naruse, Jun Mitsui, Akatsuki Kubota, So Okubo, Shuichiro Mitsuchi, Kensho Sumi, Shuichi Tanifuji, Shogo Komaki, Asuka Kitamura, Meiko Maeda, Daiki Yashita, Atsushi Sudo, Takashi Matsukawa, Masashi Hamada, Wataru Satake, Shoji Tsuji, Tatsushi Toda   +16 more
wiley   +1 more source

Greater Splanchnic Nerve Ablation in Heart Failure with Preserved Ejection Fraction: a Mini-Narrative Review of Emerging Evidence. [PDF]

Eur J Med Res
Ogieuhi IJ, Anthony CS, Ajekiigbe VO, Jiwo HL, Akinmeji A, Olaiya VO, Oyenuga AS, Oladipo TC.   +7 more
europepmc   +1 more source

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

Advanced NanoBiomed Research, EarlyView.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov, Murugan Ramalingam, Hongkai Wu, Toshinori Fujie, Yukinari Nakamura, Takeshi Hori, Yuji Nashimoto, Xuetao Shi, Hirokazu Kaji   +8 more
wiley   +1 more source

Bioprinted Excitable Tissues with Multistimulation Systems for Promoting Function and Maturation

Advanced NanoBiomed Research, EarlyView.
This review provides an overview of stimulation strategies used to enhance the functional maturation of bioprinted excitable tissues. It addresses key limitations in physiological performance of bioprinted excitable tissues, outlines major stimulation modalities—including electrical, mechanical, optical, magnetic, ultrasound, and hybrid—and examines ...
Uijung Yong, Jinseon Park, Jinah Jang
wiley   +1 more source

Atrial Mechanics in Heart Failure With Preserved Ejection Fraction: Effect of a No-Implant Interatrial Shunt. [PDF]

Circ Heart Fail
Laufer-Perl M, Flint N, Arbel Y, Alenezi F, Kittipibul V, Yaranov D, Shaburishvili T, Amin R, Fudim M.   +8 more
europepmc   +1 more source

Harnessing Machine Learning and Deep Learning Approaches for Laser‐Induced Breakdown Spectroscopy Data Analysis: A Comprehensive Review

Analysis &Sensing, EarlyView.
Laser‐induced breakdown spectroscopy (LIBS), an atomic emission technique, is widely applied in fields like geology and biology. This rapid elemental analysis method leverages computational tools to boost precision and speed up data processing. This review explores machine learning and deep learning methods for analyzing LIBS spectral data, tackling ...
Pegah Dehbozorgi, Ludovic Duponchel, Vincent Motto‐Ros, Thomas Bocklitz   +3 more
wiley   +1 more source