Results 21 to 30 of about 410,320 (404)

Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction.

New England Journal of Medicine, 2022
BACKGROUND Sodium-glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of hospitalization for heart failure and cardiovascular death among patients with chronic heart failure and a left ventricular ejection fraction of 40% or less.
S. Solomon, J. McMurray, B. Claggett, R. D. de Boer, D. DeMets, Adrian F. Hernandez, S. Inzucchi, M. Kosiborod, C. Lam, F. Martinez, Sanjiv J. Shah, Akshay S. Desai, P. Jhund, J. Bělohlávek, C. Chiang, C. Borleffs, J. Comín-Colet, D. Dobreanu, J. Drożdż, J. Fang, M. Alcocer-Gamba, Waleed Al habeeb, Yaling Han, Jose Walter Cabrera Honorio, S. Janssens, T. Katova, M. Kitakaze, B. Merkely, E. O’Meara, J. Saraiva, S. Tereshchenko, J. Thierer, M. Vaduganathan, O. Vardeny, S. Verma, V. Pham, U. Wilderäng, Natalia Zaozerska, E. Bachus, D. Lindholm, Magnus Petersson, A. Langkilde   +41 more
semanticscholar   +1 more source

Diabetes Mellitus and Heart Failure With Preserved Ejection Fraction: Role of Obesity

Frontiers in Physiology, 2022
Heart failure with preserved ejection fraction is a growing epidemic and accounts for half of all patients with heart failure. Increasing prevalence, morbidity, and clinical inertia have spurred a rethinking of the pathophysiology of heart failure with ...
Aneesh Dhore-patil, Aneesh Dhore-patil, Tariq Thannoun, Tariq Thannoun, Rohan Samson, Rohan Samson, Thierry H. Le Jemtel, Thierry H. Le Jemtel   +7 more
doaj   +1 more source

Comparing the Diagnostic Performance of HFA-PEFF and H2FPEF Scoring Systems in Heart Failure with Preserved Ejection Fraction Patients: Insights from the APOLLON Registry

Anatolian Journal of Cardiology, 2023
Background: Heart failure with preserved ejection fraction is a complex and heterogeneous clinical syndrome, poses significant diagnostic challenges.
Gurbet Özge Mert, Bülent Özlek, Eda Özlek, Hicaz Zencirkiran Ağuş, Mehmet Tekinalp, Serkan Kahraman, Cem Çil, Oğuzhan Çelik, Özcan Başaran, Volkan Doğan, Bedri Caner Kaya, İbrahim Rencüzoğulları, Altuğ Ösken, Lütfü Bekar, Mustafa Ozan Çakır, Yunus Çelik, Kadriye Memiç Sancar, Samet Sevinç, Murat Biteker, Kadir Uğur Mert   +19 more
doaj   +1 more source

Semaglutide in Patients with Heart Failure with Preserved Ejection Fraction and Obesity.

New England Journal of Medicine, 2023
BACKGROUND Heart failure with preserved ejection fraction is increasing in prevalence and is associated with a high symptom burden and functional impairment, especially in persons with obesity.
M. Kosiborod, S. Z. Abildstrom, B. Borlaug, J. Butler, S. Rasmussen, M. Davies, G. Hovingh, D. Kitzman, M. Lindegaard, D. Møller, Sanjiv J. Shah, M. Treppendahl, S. Verma, W. Abhayaratna, F. Ahmed, V. Chopra, J. Ezekowitz, Michael Fu, Hiroshi Ito, M. Lelonek, V. Melenovský, B. Merkely, Julio Núñez, E. Perna, M. Schou, M. Senni, K. Sharma, P. van der Meer, Dirk von Lewinski, Dennis Wolf, M. Petrie   +30 more
semanticscholar   +1 more source

Sacubitril/valsartan in patients with mildly reduced or preserved ejection fraction and worsening heart failure: A review

Терапевтический архив, 2023
Heart failure with mildly reduced ejection fraction and heart failure with preserved ejection fraction are associated with significant morbidity and mortality, as well as growing economic burden.
Igor V. Zhirov, Natalia V. Safronova, Sergey N. Tereshchenko   +2 more
doaj   +1 more source

Inflamed adipose tissue: A culprit underlying obesity and heart failure with preserved ejection fraction

Frontiers in Immunology, 2022
The incidence of heart failure with preserved ejection fraction is increasing in patients with obesity, diabetes, hypertension, and in the aging population. However, there is a lack of adequate clinical treatment.
Chenyu Li, Donglu Qin, Jiarui Hu, Yang Yang, Die Hu, Bilian Yu   +5 more
doaj   +1 more source

Sex differences and atrial fibrillation in heart failure with reduced versus preserved ejection fraction [PDF]

, 2021
Heart failure is a major public health problem. Patients with heart failure often experience dyspnoea, fatigue and/or have peripheral oedema. The prognosis of heart failure remains poor, with a severely impaired quality of life, frequent hospitalizations
Santema, Bernadet
core   +1 more source

Myocardial Metabolomics of Human Heart Failure With Preserved Ejection Fraction

Circulation, 2023
Background: The human heart primarily metabolizes fatty acids, and this decreases as alternative fuel use rises in heart failure with reduced ejection fraction (HFrEF).
V. Hahn, Christopher Petucci, Min-Soo Kim, K. Bedi, Hanghang Wang, Sumita Mishra, N. Koleini, Edwin J. Yoo, K. Margulies, Z. Arany, D. Kelly, D. Kass, K. Sharma   +12 more
semanticscholar   +1 more source

Sex differences in heart failure with preserved ejection fraction: From traditional risk factors to sex-specific risk factors

Women's Health, 2022
Heart failure with preserved ejection fraction has a higher prevalence in women versus men. There are several proposed mechanisms to explain this sex discrepancy including differences in cardiovascular adaptation to comorbidities and potential underlying
Gurleen Kaur, Emily Lau
doaj   +1 more source

Cardiopulmonary Test As A Component in the Diagnostic Algorithm for Heart Failure with Preserved Left Ventricular Ejection Fraction in Patients with Atrial Fibrillation [PDF]

Клиническая практика, 2023
Background: Patients with heart failure with preserved ejection fraction account for more than half of all hospitalizations because of heart failure.
Alexander S. Zotov, Elena S. Gorbacheva, Irina A. Mandel, Emil R. Sakharov, Oleg O. Shelest, Aleksandr V. Troitskiy, Robert I. Khabazov   +6 more
doaj   +1 more source