Results 91 to 100 of about 304,927 (291)

Desarrollo de moldes de prensado con recubrimientos antidesgaste

open access: yesBoletín de la Sociedad Española de Cerámica y Vidrio, 2005
Objective of the present paper has been the development of a new pressing dye concept in the field of ceramic tiles. The use of metal-ceramic composite coatings has allowed multiplying the dies life time for a factor between 2 and 3 (1.000.000 – 1.500 ...
Poyatos, A.   +3 more
doaj  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Analysis of experimental studies on the efficiency of a new mixer for molding mixtures components for the production of premix lick blocks and the final product effect

open access: yesProduction Engineering Archives
The study focuses on the design and modernization of a feed mixer and demonstrates the impact of what might seem like a non-primary machine in the technological line for producing vitamin-enriched salt lick blocks (SLB) on the quality of the final ...
Doudkin Mikhail   +5 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Research of the process of direct tobacco seeds oil expression

open access: yesНовые технологии, 2017
The article presents features of the process of pressing tobacco seeds to obtain oil. For this purpose, a press mold was developed and made and the influence of temperature and mass of seeds on the process of obtaining oil by direct pressing was studied.
E. A. Bubnov, G. I. Chalenko
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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