Results 91 to 100 of about 1,116,504 (263)

Religious pluralism and referential realism [PDF]

open access: yes, 2005
Religious plurality is a fact of our time. It cannot be avoided. Neither can it be factually acknowledged then cognitively shunned, except by enacting a most obtuse denial. Religious plurality demands a cognitive response. The pressing question is how to
Pratt, Douglas
core   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

KUALITAS FISIK WAFER TANAMAN JAGUNG DAN GAMAL DENGAN VARIASI KOMPOSISI DAN LAMA WAKTU PENGEPRESAN

open access: yesZiraa'ah: Majalah Ilmiah Pertanian
This research aimed to evaluate wafers from corn plant and Gamal compositions and the pressing times on wafer quality, namely water content, specific gravity, density, and wafer absorption capacity.
Nyimas Popi Indriani   +5 more
doaj   +1 more source

Predictive Models for Modulus of Rupture and Modulus of Elasticity of Particleboard Manufactured in Different Pressing Conditions

open access: yesHigh Temperature Materials and Processes, 2017
Determining the mechanical properties of particleboard has gained a great importance due to its increasing usage as a building material in recent years.
Tiryaki Sebahattin   +4 more
doaj   +1 more source

High-Energy Astrophysics in the 2020s and Beyond [PDF]

open access: yes, 2019
With each passing decade, we gain new appreciation for the dynamic, connected, and often violent nature of the Universe. This reality necessarily places the study of high-energy processes at the very heart of modern astrophysics.
Arnaud, Keith   +9 more
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Complex municipal solid waste sorting: approaches and methods [PDF]

open access: yes, 2015
Household waste treatment is one of the most pressing problems of our time. Waste processing and waste utilization is multifactorial ecological, economic, technological and social ...
Sydorenko, L.M.
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

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