PRESSING PAUSE: TIME BETWEEN IN VITRO FERTILIZATION (IVF) AND EMBRYO BANKING (EB) CYCLES DOES NOT IMPACT YIELD OF EMBRYOS WITH 2-PRONUCLEAR FERTILIZATION (2PNS), BLASTOCYSTS, OR EUPLOID BLASTOCYSTS [PDF]
, 2023 Jillian Pecoriello +2 more
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Applied SciencesEnsuring optimal adhesive curing during plywood and LVL (Layered Veneer Lumber) hot pressing requires accurate knowledge of internal temperature distribution, which is often difficult to assess using conventional surface-based measurements.
Szymon Kowaluk +2 more
doaj +1 more source
VP45.32: Pressing goals at the time of COVID: rebuilding patient attention and organisation of the gynecology department in a Spanish tertiary care hospital [PDF]
, 2020 T. Costas +5 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
, 2013 We construe smart meeting cinematography with a focus on professional situations such as meetings and seminars, possibly conducted in a distributed manner across socio-spatially separated groups.
Bhatt, Mehul +2 more
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Effect of Pressure, Post-Pressing Time, and Polymerization Cycle on the Degree of Conversion of Thermoactivated Acrylic Resin. [PDF]
Int J Dent, 2018 Leão RS +5 more
europepmc +1 more source